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Submit ReviewNociceptin (1-7)
Description: Bioactive metabolite of nociceptin
Biological Activity
Bioactive metabolite of nociceptin. Antagonizes nociceptin-induced hyperalgesia, with no effect on nociceptin-induced analgesia.
Technical Data
| M. Wt | 655.7 |
| Formula | C31H41N7O9 |
| Sequence | FGGFTGA |
| Storage | Desiccate at -20°C |
| CAS Number | 178249-42-8 |
| PubChem ID | 71353398 |
| InChI Key | KVTLKXLQUDUFSD-FLSSTNBBSA-N |
| Smiles | [H]N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solubility | Soluble to 2 mg/ml in water |
Product Datasheets
References
References are publications that support the biological activity of the product.
Montiel et al (1997) Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15. J.Neurochem. 68 354 PMID: 8978746
Sakurada et al (1999) Nociceptin (1-7) antagonizes nociceptin-induced hyperalgesia in mice. Br.J.Pharmacol. 128 941 PMID: 10556929
If you know of a relevant reference for Nociceptin (1-7), please let us know.
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Keywords: Nociceptin (1-7), Nociceptin (1-7) supplier, Bioactive, metabolite, nociceptin, Receptors, ORL1, OP4, NOP, Opioid, 1266, Tocris Bioscience
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