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Submit ReviewNociceptin (1-7)
Description: Bioactive metabolite of nociceptin
Biological Activity for Nociceptin (1-7)
Nociceptin (1-7) is a bioactive metabolite of nociceptin. Antagonizes nociceptin-induced hyperalgesia, with no effect on nociceptin-induced analgesia.
Technical Data for Nociceptin (1-7)
| M. Wt | 655.7 |
| Formula | C31H41N7O9 |
| Sequence | FGGFTGA |
| Storage | Desiccate at -20°C |
| CAS Number | 178249-42-8 |
| PubChem ID | 71353398 |
| InChI Key | KVTLKXLQUDUFSD-FLSSTNBBSA-N |
| Smiles | [H]N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Nociceptin (1-7)
References for Nociceptin (1-7)
References are publications that support the biological activity of the product.
Montiel et al (1997) Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15. J.Neurochem. 68 354 PMID: 8978746
Sakurada et al (1999) Nociceptin (1-7) antagonizes nociceptin-induced hyperalgesia in mice. Br.J.Pharmacol. 128 941 PMID: 10556929
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Keywords: Nociceptin (1-7), Nociceptin (1-7) supplier, Bioactive, metabolite, nociceptin, Receptors, ORL1, OP4, NOP, Opioid, 1266, Tocris Bioscience
Citations for Nociceptin (1-7)
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Currently there are no citations for Nociceptin (1-7).
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.