Nociceptin (1-7)

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Cat.No. 1266 - Nociceptin (1-7) | Phe-Gly-Gly-Phe-Thr-Gly-Ala | CAS No. 178249-42-8
Description: Bioactive metabolite of nociceptin
Literature (5)

Biological Activity

Bioactive metabolite of nociceptin. Antagonizes nociceptin-induced hyperalgesia, with no effect on nociceptin-induced analgesia.

Technical Data

M. Wt 655.7
Formula C31H41N7O9
Sequence FGGFTGA
Storage Desiccate at -20°C
CAS Number 178249-42-8
PubChem ID 71353398
Smiles [H]N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 2 mg/ml in water


References are publications that support the biological activity of the product.

Montiel et al (1997) Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15. J.Neurochem. 68 354 PMID: 8978746

Sakurada et al (1999) Nociceptin (1-7) antagonizes nociceptin-induced hyperalgesia in mice. Br.J.Pharmacol. 128 941 PMID: 10556929

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Keywords: Nociceptin (1-7), Nociceptin (1-7) supplier, Bioactive, metabolite, nociceptin, Receptors, ORL1, OP4, NOP, Opioid, 1266, Tocris Bioscience

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