L-type calcium channel blocker.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 50 mM in DMSO and to 25 mM in ethanol|
Preparing Stock Solutions
The following data is based on the product molecular weight 360.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.77 mL||13.87 mL||27.75 mL|
|5 mM||0.55 mL||2.77 mL||5.55 mL|
|10 mM||0.28 mL||1.39 mL||2.77 mL|
|50 mM||0.06 mL||0.28 mL||0.55 mL|
References are publications that support the products' biological activity.
Costa et al (1996) Characterization of a voltage-dependent L-type calcium channel from rabbit and turtle brain. Neurochem.Res. 21 537 PMID: 8726959
Watanabe et al (1995) L-type calcium channel block by highly hydrophilic dihydropyridines in single ventricular cells of guinea-pig hearts. J.Mol.Cell.Cardiol. 27 1271 PMID: 8531209
Fleming et al (2011) Chemical modulators of autophagy as biological probes and potential therapeutics. Nat.Chem.Biol. 7 9 PMID: 21164513
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Keywords: Nitrendipine, supplier, Ca2+, channel, blockers, L-type, Calcium, CaV, Channels, voltage-gated, voltage-dependent, Voltage-gated, Calcium, Channels, Autophagy, Voltage-gated, Calcium, Channels, Tocris Bioscience
2 Citations for Nitrendipine
Citations are publications that use Tocris products. Selected citations for Nitrendipine include:
Subramanian and Morozov (2011) Erk1/2 inhibit synaptic vesicle exocytosis through L-type calcium channels. J Neurosci 31 4755 PMID: 21430174
Rosenkranz et al (2009) Regulation of protease-activated receptor-1 by vasodilatory prostaglandins via NFAT. Cardiovasc Res 83 778 PMID: 19460777
Do you know of a great paper that uses Nitrendipine from Tocris? If so please let us know.
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