Naloxone fluorescein acetate

Discontinued Product

Naloxone fluorescein acetate (Cat. No. 6046) has been withdrawn from sale for commercial reasons.
Description: Fluorescent opioid antagonist; fluorescent-derivative of naloxone (Cat. No. 0599)
Chemical Name: N-(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-2-[(5α)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazinecarbothioamide acetate
Datasheet
Citations
Reviews
Literature (2)

Biological Activity for Naloxone fluorescein acetate

Naloxone fluorescein acetate is a fluorescent opioid antagonist; fluorescent derivative of naloxone (Cat. No. 0599). Excitation\emission λ ~ 492\517 nm at pH 10.

Technical Data for Naloxone fluorescein acetate

M. Wt 790.84
Formula C40H34N4O8S.C2H4O2
Storage Store at -20°C
CAS Number 2080300-52-1
PubChem ID 122705994
InChI Key DRNYJSGWOSUNLJ-KYTOOIOKSA-N
Smiles [H][C@@]12OC3=C(C=CC4=C3[C@@]15CCN([C@](C4)([C@@]5(CC/C2=N\NC(NC6=CC=C7C(C(OC78C9=CC=C(C=C9OC%10=CC(O)=CC=C8%10)O)=O)=C6)=S)O)[H])CC=C)O.CC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Naloxone fluorescein acetate

Certificate of Analysis / Product Datasheet
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References for Naloxone fluorescein acetate

References are publications that support the biological activity of the product.

Friesen et al (2014) Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma. Cell Cycle 13 1560 PMID: 24626197

Keywords: Naloxone fluorescein acetate, Naloxone fluorescein acetate supplier, Fluorescent, opioid, receptor, antagonists, antagonism, Miscellaneous/Non-selective, Opioids, Receptor, Probes, 6046, Tocris Bioscience

Citations for Naloxone fluorescein acetate

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Currently there are no citations for Naloxone fluorescein acetate.

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Literature in this Area

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