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Submit ReviewNaloxone fluorescein acetate is a fluorescent opioid antagonist; fluorescent-derivative of naloxone (Cat. No. 0599). Excitation\emission λ ~ 492\517 nm at pH 10.
M. Wt | 790.84 |
Formula | C40H34N4O8S.C2H4O2 |
Storage | Store at -20°C |
CAS Number | 2080300-52-1 |
PubChem ID | 122705994 |
InChI Key | DRNYJSGWOSUNLJ-KYTOOIOKSA-N |
Smiles | [H][C@@]12OC3=C(C=CC4=C3[C@@]15CCN([C@](C4)([C@@]5(CC/C2=N\NC(NC6=CC=C7C(C(OC78C9=CC=C(C=C9OC%10=CC(O)=CC=C8%10)O)=O)=C6)=S)O)[H])CC=C)O.CC(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
DMSO | 0.5 | 1 |
The following data is based on the product molecular weight 790.84. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.01 mM | 126.45 mL | 632.24 mL | 1264.48 mL |
0.05 mM | 25.29 mL | 126.45 mL | 252.9 mL |
0.1 mM | 12.64 mL | 63.22 mL | 126.45 mL |
0.5 mM | 2.53 mL | 12.64 mL | 25.29 mL |
References are publications that support the biological activity of the product.
Friesen et al (2014) Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma. Cell Cycle 13 1560 PMID: 24626197
If you know of a relevant reference for Naloxone fluorescein acetate, please let us know.
Keywords: Naloxone fluorescein acetate, Naloxone fluorescein acetate supplier, Fluorescent, opioid, receptor, antagonists, antagonism, Miscellaneous/Non-selective, Opioids, Receptor, Probes, 6046, Tocris Bioscience
Citations are publications that use Tocris products.
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