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Biological Activity for Nalmefene hydrochloride
Nalmefene hydrochloride is an opioid receptor antagonist; displays a longer half life than Naloxone. Exhibits neuroprotective effects after traumatic brain injury in the rat.
Compound Libraries for Nalmefene hydrochloride
Technical Data for Nalmefene hydrochloride
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Nalmefene hydrochloride
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Nalmefene hydrochloride
The following data is based on the product molecular weight 375.89. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.66 mL||13.3 mL||26.6 mL|
|5 mM||0.53 mL||2.66 mL||5.32 mL|
|10 mM||0.27 mL||1.33 mL||2.66 mL|
|50 mM||0.05 mL||0.27 mL||0.53 mL|
Product Datasheets for Nalmefene hydrochloride
References for Nalmefene hydrochloride
References are publications that support the biological activity of the product.
Vink et al (1990) Opiate antagonist nalmefene improves intracellular free Mg2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats. J.Neurosci. 10 3524 PMID: 2230942
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Keywords: Nalmefene hydrochloride, Nalmefene hydrochloride supplier, opioid, receptor, antagonist, antagonists, Miscellaneous/Non-selective, Opioids, 4085, Tocris Bioscience
Citations for Nalmefene hydrochloride
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Reviews for Nalmefene hydrochloride
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.