N-Benzylnaltrindole hydrochloride

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Cat.No. 0754 - N-Benzylnaltrindole hydrochloride | C33H32N2O3.HCl | CAS No. 1206487-81-1
Description: Selective non-peptide δ2 antagonist
Chemical Name: 1'-Benzyl-17-(cyclopropylmethyl)-6,7-didehydro-4,5a-epoxy-3,14-dihydroxyindolo[2',3':6,7]morphinan hydrochloride
Datasheet
Citations
Reviews
Literature

Biological Activity

Potent δ2-selective opioid receptor antagonist with a long duration of action in vivo.

Technical Data

M. Wt 541.09
Formula C33H32N2O3.HCl
Storage Store at RT
CAS Number 1206487-81-1
PubChem ID 90479740
InChI Key KDEBSUYWJUBPCB-ZHYTUUPESA-N
Smiles O[C@@]24[C@]3([C@@H]8C(N6CC7=CC=CC=C7)=C(C5=C6C=CC=C5)C4)C1=C(O8)C(O)=CC=C1CC2N(CC9CC9)CC3.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 54.11 100

Preparing Stock Solutions

The following data is based on the product molecular weight 541.09. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.85 mL 9.24 mL 18.48 mL
5 mM 0.37 mL 1.85 mL 3.7 mL
10 mM 0.18 mL 0.92 mL 1.85 mL
50 mM 0.04 mL 0.18 mL 0.37 mL

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References

References are publications that support the biological activity of the product.

Korlipara et al (1994) N-Benzylnaltrindoles as long acting δ-opioid receptor antagonists. J.Med.Chem. 37 1882 PMID: 8021928


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Keywords: N-Benzylnaltrindole hydrochloride, N-Benzylnaltrindole hydrochloride supplier, δ2-opioid, delta2-opioid, selective, non-peptide, antagonists, DOP, Receptors, OP1, Delta, Opioid, 0754, Tocris Bioscience

Citations for N-Benzylnaltrindole hydrochloride

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