MAPK Cascade Inhibitor Tocriset™

Pricing Availability Delivery Time Qty

Contents of Tocriset:

Cat.No. Product Name / Activity
1144U0126
potent and selective inhibitor of MAP2K
1202SB 203580
selective inhibitor of p38 MAPK
1213PD 98059
inhibitor of MAPKK / MEK
1321ZM 336372
potent, selective c-Raf inhibitor
1110Genistein
epidermal growth factor receptor (EGFR) kinase inhibitor
Description: Selection of 5 MAPK cascade inhibitors (Cat. Nos. 1110, 1213, 1321, 1144 and 1202)
Datasheet
Citations
Literature

Biological Activity

Contains the listed products which can be used to inhibit various kinases in the MAPK signal transduction pathway. The products are supplied either as a solid (U0126) or pre-dissolved in DMSO at a stock concentration of 10 mM in 0.5 ml.

Technical Data

Tocrisets contain 3-5 ligands supplied as lyophilized solids or pre-dissolved in DMSO at a specified concentration. Lyophilized solids have been freeze-dried (approximately 0.5-2 mg per vial) so that addition of 0.5 or 1 ml of solvent produces a stock concentration of 10 or 5 mM respectively.

Please see individual product listings for specific technical data and certificate of analysis.

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

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Citations for MAPK Cascade Inhibitor Tocriset™

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Literature in this Area

Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis