MAPK Cascade Inhibitor Tocriset™
Contents of Tocriset:
|Cat. No.||Product Name / Activity|
|epidermal growth factor receptor (EGFR) kinase inhibitor|
|potent, selective c-Raf inhibitor|
|potent and selective inhibitor of MAP2K|
|selective inhibitor of p38 MAPK|
|inhibitor of MAPKK / MEK|
Contains the listed products which can be used to inhibit various kinases in the MAPK signal transduction pathway. The products are supplied either as a solid (U0126) or pre-dissolved in DMSO at a stock concentration of 10 mM in 0.5 ml.
Tocrisets contain 3-5 ligands supplied as lyophilized solids or pre-dissolved in DMSO at a specified concentration. Lyophilized solids have been freeze-dried (approximately 0.5-2 mg per vial) so that addition of 0.5 or 1 ml of solvent produces a stock concentration of 10 or 5 mM respectively.
Please see individual product listings for specific technical data and certificate of analysis.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
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Literature in this Area
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