MAP4

Discontinued Product

MAP4 (Cat. No. 0711) has been withdrawn from sale for commercial reasons.
Description: Potent group II mGlu agonist; also group III mGlu antagonist
Chemical Name: (S)-2-Amino-2-methyl-4-phosphonobutanoic acid
Purity: ≥96% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (4)

Biological Activity for MAP4

MAP4 is a selective group III metabotropic glutamate receptor antagonist in some electrophysiological systems. Group II/group III agonist in certain neurochemical systems.

Technical Data for MAP4

M. Wt 197.13
Formula C5H12NO5P
Storage Store at RT
Purity ≥96% (HPLC)
CAS Number 157381-42-5
PubChem ID 1795545
InChI Key HONKEGXLWUDTCF-YFKPBYRVSA-N
Smiles N[C@](CCP(O)(O)=O)(C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for MAP4

Certificate of Analysis / Product Datasheet
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View Related Products by Product Action

View all Glutamate (Metabotropic) Group II Receptor Agonists

Keywords: MAP4, MAP4 supplier, Potent, group, II, mGlur, agonists, specific, III, antagonists, Selective, potent, Group, Receptors, mGlu2, mGlu3, mGluR2, mGluR3, Glutamate, Metabotropic, mGlu4, mGluR4, mGlu6, mGluR6, mGlu7, mGluR7, mGlu8, mGlkuR8, (Metabotropic), 0711, Tocris Bioscience

1 Citation for MAP4

Citations are publications that use Tocris products. Selected citations for MAP4 include:

Piet et al (2004) Physiological contribution of the astrocytic environment of neurons to intersynaptic crosstalk. J Neurosci 101 2151 PMID: 14766975


Reviews for MAP4

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Metabotropic Glutamate Receptors Scientific Review

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.

Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.