LY 303511

Discontinued Product

LY 303511 (Cat. No. 2418) has been withdrawn from sale for commercial reasons.
Description: Negative control of LY 294002 (Cat. No. 1130)
Chemical Name: 2-(1-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews

Biological Activity for LY 303511

LY 303511 is a negative control compound for LY 294002 PI 3-kinase inhibitory activity. Blocks voltage-gated potassium (Kv) channels (IC50 = 64.6 μM) and inhibits IL-1β-stimulated NF-κB activation, attenuating MCP-1 expression. Antiproliferative. Also inhibits the BET bromodomain proteins BRD2, BRD3 and BRD4.

Active Analog also available.

Technical Data for LY 303511

M. Wt 306.36
Formula C19H18N2O2
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 154447-38-8
PubChem ID 3971
InChI Key NGAGMBNBKCDCDJ-UHFFFAOYSA-N
Smiles O=C1C=C(OC2=C(C=CC=C12)C1=CC=CC=C1)N1CCNCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Keywords: LY 303511, LY 303511 supplier, Negative, control, LY, 294002, LY294002, PI3K, Phosphoinositide, PI, 3-Kinases, PIP2, Inositol, Lipids, LY303511, BETbromodomains, inhibitors, inhibits, BRD2, BRD3, BRD4, 3-Kinase, Bromodomains, 2418, Tocris Bioscience

Citations for LY 303511

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