Lorazepam

Discontinued Product

Lorazepam (Cat. No. 3087) has been withdrawn from sale for commercial reasons.
Description: Ligand at benzodiazepine site
Chemical Name: 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepine-2-one
Datasheet
Citations
Reviews
Literature (2)

Biological Activity for Lorazepam

Ligand at the GABAA receptor benzodiazepine modulatory site. Anxiolytic, anticonvulsant and sedative/hypnotic agent.

Technical Data for Lorazepam

M. Wt 321.16
Formula C15H10Cl2N2O2
Storage Store at RT
CAS Number 846-49-1
PubChem ID 3958
InChI Key DIWRORZWFLOCLC-UHFFFAOYSA-N
Smiles O=C2C(O)N=C(C3=CC=CC=C3Cl)C1=CC(Cl)=CC=C1N2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for Lorazepam

References are publications that support the biological activity of the product.

Bonavita et al (2002) Tolerance to the sedative effect of L.pam correlates with a diminution in cortical release and affinity for glutamate. Neuropharmacol. 42 619

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Keywords: Lorazepam, Lorazepam supplier, Acts, benzodiazepine, modulatory, site, GABAA, Receptors, 3087, Tocris Bioscience

Citations for Lorazepam

Citations are publications that use Tocris products.

Currently there are no citations for Lorazepam.

Reviews for Lorazepam

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.