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Submit ReviewKynurenic acid sodium salt
Description: Sodium salt of kynurenic acid (Cat. No. 0223)
Chemical Name: 4-Hydroxyquinoline-2-carboxylic acid sodium salt
Purity: ≥98% (HPLC)
Biological Activity for Kynurenic acid sodium salt
Kynurenic acid sodium salt is a sodium salt of kynurenic acid (Cat. No. 0223), a broad spectrum EAA antagonist.
Compound Libraries for Kynurenic acid sodium salt
Kynurenic acid sodium salt is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.
Technical Data for Kynurenic acid sodium salt
| M. Wt | 211.15 |
| Formula | C10H6NNaO3 |
| Storage | Desiccate at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 2439-02-3 |
| PubChem ID | 52974250 |
| InChI Key | RCAZGXKUQDXSSK-UHFFFAOYSA-M |
| Smiles | [Na+].OC1=CC(=NC2=CC=CC=C12)C([O-])=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Kynurenic acid sodium salt
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 21.11 | 100 | |
| DMSO | 10.56 | 50 |
Preparing Stock Solutions for Kynurenic acid sodium salt
The following data is based on the product molecular weight 211.15. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.74 mL | 23.68 mL | 47.36 mL |
| 5 mM | 0.95 mL | 4.74 mL | 9.47 mL |
| 10 mM | 0.47 mL | 2.37 mL | 4.74 mL |
| 50 mM | 0.09 mL | 0.47 mL | 0.95 mL |
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Product Datasheets for Kynurenic acid sodium salt
References for Kynurenic acid sodium salt
References are publications that support the biological activity of the product.
Perkins and Stone (1982) An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res. 247 184 PMID: 6215086
Pittaluga et al (1997) The 'kynurenate test', a biochemical assay for putative cognition enhancers. J.Pharmacol.Exp.Ther. 283 82 PMID: 9336311
Wang et al (2006) Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J.Biol.Chem. 281 22021 PMID: 16754668
Stone and Burton (1988) NMDA receptors and ligands in the vertebrate CNS. Progr.Neurobiol. 30 333 PMID: 2830636
If you know of a relevant reference for Kynurenic acid sodium salt, please let us know.
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Keywords: Kynurenic acid sodium salt, Kynurenic acid sodium salt supplier, Broad, spectrum, EAA, antagonists, Glutamate, Ionotropic, Non-Selective, iGluR, Receptors, mGlur, Metabotropic, Non-selective, GPR35, 3694, Tocris Bioscience
Citations for Kynurenic acid sodium salt
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