Kynurenic acid sodium salt

Pricing Availability Delivery Time Qty
Cat.No. 3694 - Kynurenic acid sodium salt | C10H6NNaO3 | CAS No. 2439-02-3
Description: Sodium salt of kynurenic acid (Cat. No. 0223)
Chemical Name: 4-Hydroxyquinoline-2-carboxylic acid sodium salt
Purity: ≥99% (HPLC)

Biological Activity

Sodium salt of kynurenic acid (Cat. No. 0223), a broad spectrum EAA antagonist.

Technical Data

M. Wt 211.15
Formula C10H6NNaO3
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 2439-02-3
PubChem ID 52974250
Smiles [Na+].OC1=CC(=NC2=CC=CC=C12)C([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 10.56 50
water 21.11 100

Preparing Stock Solutions

The following data is based on the product molecular weight 211.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.74 mL 23.68 mL 47.36 mL
5 mM 0.95 mL 4.74 mL 9.47 mL
10 mM 0.47 mL 2.37 mL 4.74 mL
50 mM 0.09 mL 0.47 mL 0.95 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet


References are publications that support the products' biological activity.

Perkins and Stone (1982) An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res. 247 184 PMID: 6215086

Pittaluga et al (1997) The 'kynurenate test', a biochemical assay for putative cognition enhancers. J.Pharmacol.Exp.Ther. 283 82 PMID: 9336311

Wang et al (2006) Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J.Biol.Chem. 281 22021 PMID: 16754668

Stone and Burton (1988) NMDA receptors and ligands in the vertebrate CNS. Progr.Neurobiol. 30 333 PMID:

If you know of a relevant reference for Kynurenic acid sodium salt, please let us know.

View Related Products by Product Action

View all Non-selective Ionotropic Glutamate Antagonists

Keywords: Kynurenic acid sodium salt, supplier, Broad, spectrum, EAA, antagonists, Glutamate, Ionotropic, Non-Selective, iGluR, Receptors, mGlur, Metabotropic, Non-selective, Ionotropic, Glutamate, Tocris Bioscience

Citations for Kynurenic acid sodium salt

Citations are publications that use Tocris products.

Currently there are no citations for Kynurenic acid sodium salt. Do you know of a great paper that uses Kynurenic acid sodium salt from Tocris? If so please let us know.

Commented out for usability testing


TODO: Add Reviews

Literature in this Area


Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.


Parkinson's Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.

Pathways for Kynurenic acid sodium salt


TODO: Add Protocols