Kynurenic acid sodium salt

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Cat.No. 3694 - Kynurenic acid sodium salt | C10H6NNaO3 | CAS No. 2439-02-3
Description: Sodium salt of kynurenic acid (Cat. No. 0223)
Chemical Name: 4-Hydroxyquinoline-2-carboxylic acid sodium salt
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (5)

Biological Activity

Sodium salt of kynurenic acid (Cat. No. 0223), a broad spectrum EAA antagonist.

Technical Data

M. Wt 211.15
Formula C10H6NNaO3
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 2439-02-3
PubChem ID 52974250
InChI Key RCAZGXKUQDXSSK-UHFFFAOYSA-M
Smiles [Na+].OC1=CC(=NC2=CC=CC=C12)C([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 21.11 100
DMSO 10.56 50

Preparing Stock Solutions

The following data is based on the product molecular weight 211.15. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.74 mL 23.68 mL 47.36 mL
5 mM 0.95 mL 4.74 mL 9.47 mL
10 mM 0.47 mL 2.37 mL 4.74 mL
50 mM 0.09 mL 0.47 mL 0.95 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Perkins and Stone (1982) An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res. 247 184 PMID: 6215086

Pittaluga et al (1997) The 'kynurenate test', a biochemical assay for putative cognition enhancers. J.Pharmacol.Exp.Ther. 283 82 PMID: 9336311

Wang et al (2006) Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J.Biol.Chem. 281 22021 PMID: 16754668

Stone and Burton (1988) NMDA receptors and ligands in the vertebrate CNS. Progr.Neurobiol. 30 333


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Citations for Kynurenic acid sodium salt

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