KLD 12

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Cat.No. 6797 - KLD 12 | Ac-Lys-Leu-Asp-Leu-Lys-Leu-Asp-Leu-Lys-Leu-Asp-Leu-NH2 | CAS No. 800379-47-9
Description: Self-assembling peptide; forms hydrogel to support cell growth
Datasheet
Citations
Reviews
Literature (4)

Biological Activity

Self-assembling peptide that forms a hydrogel matrix to support growth of cells in the presence of an ionic solution. Enhances chondrogenic differentiation of bone marrow stromal cells (BMSCs).

Technical Data

M. Wt 1467.81
Formula C68H122N16O19
Sequence KLDLKLDLKLDL

(Modifications: Lys-1 = N-terminal Ac, Leu-12 = C-terminal amide)

Storage Store at -20°C
CAS Number 800379-47-9
InChI Key JXVKXIMEQMJEAG-PEWBXTNBSA-N
Smiles NCCCC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC(C)C)=O)CC(O)=O)=O)CC(C)C)=O)CCCCN)=O)CC(C)C)=O)CC(O)=O)=O)CC(C)C)=O)CCCCN)=O)CC(C)C)=O)CC(O)=O)=O)CC(C)C)=O)NC(C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 0.50 mg/ml in water

References

References are publications that support the biological activity of the product.

Kisiday et al (2002) Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair. Proc.Natl.Acad.Sci.U.S.A. 99 9996 PMID: 12119393

Tripathi et al (2015) Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties. Biomaterials. 56 92 PMID: 25934283


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Keywords: KLD 12, KLD 12 supplier, KLD12, peptide, hydrogel, matrix, self, assembly, stem, cell, growth, Stem, Cell, Proliferation, 6797, Tocris Bioscience

Citations for KLD 12

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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