KHS 101 hydrochloride
Selective inducer of neuronal differentiation; induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50 ~1 μM). Suppresses astrocyte formation. Also induces acceleration of neuronal differentiation in the hippocampal dentate gyrus in vivo.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 375.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||5.32 mL||26.6 mL||53.2 mL|
|2.5 mM||1.06 mL||5.32 mL||10.64 mL|
|5 mM||0.53 mL||2.66 mL||5.32 mL|
|25 mM||0.11 mL||0.53 mL||1.06 mL|
References are publications that support the biological activity of the product.
Wurdak et al (2010) A small molecule accelerates neuronal differentiation in the adult rat. Proc.Natl.Acad.Sci.USA. 107 16542 PMID: 20823227
If you know of a relevant reference for KHS 101 hydrochloride, please let us know.
Keywords: KHS 101 hydrochloride, KHS 101 hydrochloride supplier, KHS101, hydrochloride, transforming, acidic, coiled-coil-containing, protein, 3, TACC3, NPC, hippocampal, neural, progenitors, cells, neuronal, differentiation, maturing, neurons, differentiated, selective, activators, [1262770-73-9], Neural, Stem, Cells, 4888, Tocris Bioscience
Citations for KHS 101 hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for KHS 101 hydrochloride. Do you know of a great paper that uses KHS 101 hydrochloride from Tocris? Please let us know.
Reviews for KHS 101 hydrochloride
There are currently no reviews for this product. Be the first to review KHS 101 hydrochloride and earn rewards!
Have you used KHS 101 hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Stem Cells Scientific Review
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
Stem Cell Workflow PosterNew
Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.