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KHS 101 hydrochloride
Biological Activity for KHS 101 hydrochloride
KHS 101 hydrochloride is a selective inducer of neuronal differentiation; induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50 ~1 μM). Suppresses astrocyte formation. Also induces acceleration of neuronal differentiation in the hippocampal dentate gyrus in vivo.
Compound Libraries for KHS 101 hydrochloride
Technical Data for KHS 101 hydrochloride
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for KHS 101 hydrochloride
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for KHS 101 hydrochloride
The following data is based on the product molecular weight 375.92. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||5.32 mL||26.6 mL||53.2 mL|
|2.5 mM||1.06 mL||5.32 mL||10.64 mL|
|5 mM||0.53 mL||2.66 mL||5.32 mL|
|25 mM||0.11 mL||0.53 mL||1.06 mL|
Product Datasheets for KHS 101 hydrochloride
References for KHS 101 hydrochloride
References are publications that support the biological activity of the product.
Wurdak et al (2010) A small molecule accelerates neuronal differentiation in the adult rat. Proc.Natl.Acad.Sci.USA. 107 16542 PMID: 20823227
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1 Citation for KHS 101 hydrochloride
Citations are publications that use Tocris products. Selected citations for KHS 101 hydrochloride include:
Henrik Daa et al (2021) Metabolic impairment of non-small cell lung cancers by mitochondrial HSPD1 targeting. J Exp Clin Cancer Res 40 248 PMID: 34364401
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
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