You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for IT 901
IT 901 is a c-Rel inhibitor (IC50 = 3 μM). Inhibits IL-2 expression in activated T-cells in vitro. Reduces severity of graft-versus-host disease following hematopoietic stem cell transplant (HSCT) and inhibits growth of human B-cell lymphoma xenografts in mice. Inhibits the oxidative stress response in lymphoma cells.
Technical Data for IT 901
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for IT 901
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for IT 901
The following data is based on the product molecular weight 342.37. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.92 mL||14.6 mL||29.21 mL|
|5 mM||0.58 mL||2.92 mL||5.84 mL|
|10 mM||0.29 mL||1.46 mL||2.92 mL|
|50 mM||0.06 mL||0.29 mL||0.58 mL|
References for IT 901
References are publications that support the biological activity of the product.
Shono et al (2016) Characterization of a c-Rel inhibitor that mediates anticancer properties in hematologic malignancies by blocking NF-κB-controlled oxidative stress responses. Cancer Res. 76 377 PMID: 26744524
If you know of a relevant reference for IT 901, please let us know.
View Related Products by Product Action
Keywords: IT 901, IT 901 supplier, IT901, NF-KB, NF-KappaB, NF-κB, c-Rel, subunit, inhibitors, inhibits, oxidative, stress, response, anticancer, NF-kB/IkB, 5846, Tocris Bioscience
Citations for IT 901
Citations are publications that use Tocris products.
Currently there are no citations for IT 901. Do you know of a great paper that uses IT 901 from Tocris? Please let us know.
Reviews for IT 901
There are currently no reviews for this product. Be the first to review IT 901 and earn rewards!
Have you used IT 901?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.