Home / Product Type / Fluorescence Imaging / Fluorescent Dyes / Other Fluorescent Dyes / Hydroxystilbamidine bis(methanesulfonate)

Hydroxystilbamidine bis(methanesulfonate)

Cat. No. 6406 Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Cat.No. 6406 - Hydroxystilbamidine bis(methanesulfonate) | C16H16N4O.2CH4O3S | CAS No. 223769-64-0
Description: Fluorescent cationic dye; neuronal tracer
Chemical Name: 4-[2-[4-(Aminoiminomethyl)phenyl]ethenyl]-3-hydroxybenzenecarboximidamide bis(methanesulfonate)
Purity: ≥95% (HPLC)
Datasheet
Citations
Reviews
Literature (1)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Fluorescent cationic dye commonly used as a neuronal tracer; exhibits retrograde axonal transport. Displays different fluorescence emission wvelenghts when bound to DNA compared to RNA. Visualize with an ultraviolet excitation filter. Gold color is emitted when tissue is processed with a neutral pH buffer while blue/bright white is emitted when an acidic pH buffer is used.

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

Spectral Viewer

Technical Data

M. Wt 472.54
Formula C16H16N4O.2CH4O3S
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 223769-64-0
PubChem ID 16212515
InChI Key FKNGLYONHKRGRM-QKBHCULISA-N
Smiles NC(C(C=C1)=CC=C1/C=C/C2=C(O)C=C(C(N)=N)C=C2)=N.CS(=O)(O)=O.CS(=O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 23.63 50

Preparing Stock Solutions

The following data is based on the product molecular weight 472.54. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.23 mL 21.16 mL 42.32 mL
2.5 mM 0.85 mL 4.23 mL 8.46 mL
5 mM 0.42 mL 2.12 mL 4.23 mL
25 mM 0.08 mL 0.42 mL 0.85 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References

References are publications that support the biological activity of the product.

Chen et al (2012) Motor fiber organization in the extratemporal trunk of the facial nerve in rats: A retrograde Fluoro-Gold study. Exp.Ther.Med. 4 844 PMID: 23226737

Murgatroyd et al (1982) 2-hydroxystilbamidine isethionate: a new fluorochrome for use in general pathology. I. The selective staining of DNA, mucosubstances and elastic fibres. Histochemistry 74 107 PMID: 6177666

Buys et al (1995) (-)-Deprenyl increases the survival of rat retinal ganglion cells after optic nerve crush. Curr Eye Res. 14 119 PMID: 7768105

Day et al (2001) A beta-fiber intensity stimulation of chronically constricted median nerve induces c-fos expression in thalamic projection neurons of the cuneate nucleus in rats with behavioral signs of neuropathic pain. Brain Res. 895 194 PMID: 11259778

If you know of a relevant reference for Hydroxystilbamidine bis(methanesulfonate), please let us know.

View Related Products by Target

Keywords: Hydroxystilbamidine bis(methanesulfonate), Hydroxystilbamidine bis(methanesulfonate) supplier, fluorescent, neuronal, dyes, retrograde, axonal, tracers, Fluoro, Gold, DNA, RNA, probe, Other, Fluorescent, Dyes, 6406, Tocris Bioscience

Citations for Hydroxystilbamidine bis(methanesulfonate)

Citations are publications that use Tocris products.

Currently there are no citations for Hydroxystilbamidine bis(methanesulfonate). Do you know of a great paper that uses Hydroxystilbamidine bis(methanesulfonate) from Tocris? Please let us know.

Reviews for Hydroxystilbamidine bis(methanesulfonate)

There are currently no reviews for this product. Be the first to review Hydroxystilbamidine bis(methanesulfonate) and earn rewards!

Have you used Hydroxystilbamidine bis(methanesulfonate)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

New Product Guide

New Product Guide [Spring/Summer 2019]

Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Chemogenetics
  • Epigenetics
  • Fluorescent Imaging
  • PROTACs
  • Signal Transduction
  • Stem Cells