Hydroxystilbamidine bis(methanesulfonate)

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Cat.No. 6406 - Hydroxystilbamidine bis(methanesulfonate) | C16H16N4O.2CH4O3S | CAS No. 223769-64-0
Description: Fluorescent cationic dye; neuronal tracer
Chemical Name: 4-[2-[4-(Aminoiminomethyl)phenyl]ethenyl]-3-hydroxybenzenecarboximidamide bis(methanesulfonate)
Purity: ≥95% (HPLC)

Biological Activity

Fluorescent cationic dye commonly used as a neuronal tracer. Exhibits retrograde axonal transport. Visualize with an ultraviolet excitation filter. Gold color is emitted when tissue is processed with a neutral pH buffer while blue/bright white is emitted when an acidic pH buffer is used.

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Technical Data

M. Wt 472.54
Formula C16H16N4O.2CH4O3S
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 223769-64-0
PubChem ID 16212515
Smiles NC(C(C=C1)=CC=C1/C=C/C2=C(O)C=C(C(N)=N)C=C2)=N.CS(=O)(O)=O.CS(=O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 23.63 50

Preparing Stock Solutions

The following data is based on the product molecular weight 472.54. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.23 mL 21.16 mL 42.32 mL
2.5 mM 0.85 mL 4.23 mL 8.46 mL
5 mM 0.42 mL 2.12 mL 4.23 mL
25 mM 0.08 mL 0.42 mL 0.85 mL

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References are publications that support the biological activity of the product.

Chen et al (2012) Motor fiber organization in the extratemporal trunk of the facial nerve in rats: A retrograde Fluoro-Gold study. Exp.Ther.Med. 4 844 PMID: 23226737

If you know of a relevant reference for Hydroxystilbamidine bis(methanesulfonate), please let us know.

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Citations for Hydroxystilbamidine bis(methanesulfonate)

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New Product Guide (Fall/Winter 2018/2019)

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