You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
STAT5-SUMO protein-protein interaction inhibitor. Blocks SUMOylation of phosphorylated STAT5. Reactivates latent HIV-1 reservoir in central memory T cells (TCM). Increases viral release by ~2.7-fold at a concentration of 100 μM in combination with IL-2 compared to unstimulated cells; reduces size of latent HIV-1 reservoir in vitro.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 163.14. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||6.13 mL||30.65 mL||61.3 mL|
|5 mM||1.23 mL||6.13 mL||12.26 mL|
|10 mM||0.61 mL||3.06 mL||6.13 mL|
|50 mM||0.12 mL||0.61 mL||1.23 mL|
References are publications that support the biological activity of the product.
Bosque et al (2017) Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation. Cell Rep. 18 1324 PMID: 28147284
If you know of a relevant reference for HODHBt, please let us know.
Keywords: HODHBt, HODHBt supplier, STAT5, SUMO, SUMOylation, protein-protein, interactions, inhibitors, inhibits, HIV-1, reservoir, STAT, HIV, 6994, Tocris Bioscience
Citations for HODHBt
Citations are publications that use Tocris products.
Currently there are no citations for HODHBt. Do you know of a great paper that uses HODHBt from Tocris? Please let us know.
Reviews for HODHBt
There are currently no reviews for this product. Be the first to review HODHBt and earn rewards!
Have you used HODHBt?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.