Selective Epac2 inhibitor (IC50 = 0.3 μM). Displays no effect on Epac1. Blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 277.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||7.21 mL||36.05 mL||72.1 mL|
|2.5 mM||1.44 mL||7.21 mL||14.42 mL|
|5 mM||0.72 mL||3.61 mL||7.21 mL|
|25 mM||0.14 mL||0.72 mL||1.44 mL|
References are publications that support the biological activity of the product.
Chen et al (2013) Identification and characterization of small molecules as potent and specific EPAC2 antagonists. J.Med.Chem. 56 952 PMID: 23286832
If you know of a relevant reference for HJC 0350, please let us know.
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