H3K4(Me3) (1-20)

Pricing Availability Delivery Time Qty
Cat.No. 6216 - H3K4(Me3) (1-20) | Ala-Arg-Thr-Lys(Me3)-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu
Description: Histone H3 peptide; substrate for methyltransferase/demethylase enzymes
Datasheet
Citations
Literature

Biological Activity

Histone peptide. Substrate for methyltransferase/demethylase enzymes. Peptide derived from human histone isotype 3.1.

Technical Data

M. Wt 2226.62
Formula C94H174N35O27
Sequence ARTKQTARKSTGGKAPRKQL

(Modifications: Lys-4 = Lys(Me3))

Storage Store at -20°C
InChI Key BXOURZCZYXJRTF-XGLQKYDCNA-N
Smiles [H]N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCC[N](C)(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 2226.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.45 mL 2.25 mL 4.49 mL
5 mM 0.09 mL 0.45 mL 0.9 mL
10 mM 0.04 mL 0.22 mL 0.45 mL
50 mM 0.01 mL 0.04 mL 0.09 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Mulder et al (2017) Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex. Nucleic Acids Res. 35 2428 PMID: 17392337


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Keywords: H3K4(Me3) (1-20), supplier, histone, H3, peptide, demethylases, demethylation, methyltransferases, methylation, enzyme, substrate, Histone, Peptides, Enzyme, Substrates, /, Activators, Enzyme, Substrates, /, Activators, Tocris Bioscience

Citations for H3K4(Me3) (1-20)

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