GSHtracer

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Cat.No. 6594 - GSHtracer | C21H21N3O3 | CAS No. 1479071-34-5
Description: Radiometric glutathione (GSH) probe
Chemical Name: 2-Cyano-N,N-dimethyl-3-(2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-10-yl)-2-propenamide
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Radiometric probe for measuring of glutathione (GSH) levels. Upon GSH binding, excitation/emission maximum λ shifts from 520/580 nm to 430/510 nm. F510/F580 ratio correlates with GSH concentration.

Technical Data

M. Wt 363.41
Formula C21H21N3O3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1479071-34-5
PubChem ID 102344531
InChI Key YCXQIYZKBAKCHQ-LFIBNONCSA-N
Smiles CN(C(/C(C#N)=C/C1=CC2=CC3=C4N(CCCC4=C2OC1=O)CCC3)=O)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 7.27 20

Preparing Stock Solutions

The following data is based on the product molecular weight 363.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 13.76 mL 68.79 mL 137.59 mL
1 mM 2.75 mL 13.76 mL 27.52 mL
2 mM 1.38 mL 6.88 mL 13.76 mL
10 mM 0.28 mL 1.38 mL 2.75 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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References

References are publications that support the biological activity of the product.

Jeong et al (2018) Real-time monitoring of glutathione in living cells reveals that high glutathione levels are required to maintain stem cell function. Stem Cell Reports 10 600 PMID: 29307581


If you know of a relevant reference for GSHtracer, please let us know.

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Citations for GSHtracer

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Literature in this Area

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New Product Guide

New Product Guide (Spring/Summer 2018)

Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.

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