GBLD 345

Discontinued Product

GBLD 345 (Cat. No. 0770) has been withdrawn from sale for commercial reasons.
Description: High affinity benzodiazepine agonist
Chemical Name: 2-(4-Aminophenyl)-3-methoxy-6-(3-methoxyphenyl)-methylimidazo[1,2-b]pyridazine
Datasheet
Citations
Reviews
Literature (2)

Biological Activity for GBLD 345

A high affinity benzodiazepine agonist (IC50 against diazepam = 1 nM).

Technical Data for GBLD 345

M. Wt 375.43
Formula C21H21N5O2
Storage Store at RT
CAS Number 122479-08-7
Smiles NC(C=C4)=CC=C4C2=C(OC)N(C(C=C3)=N2)N=C3NCC1=CC=CC(OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for GBLD 345

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for GBLD 345

References are publications that support the biological activity of the product.

Davies et al (1992) Substituted imidazo[1,2-b]pyridazines. New compounds with activity at central and peripheral benzodiazepine receptors. Biochem.Pharmacol. 44 1555 PMID: 1358075

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Keywords: GBLD 345, GBLD 345 supplier, High, affinity, benzodiazepine, agonists, GABAA, Receptors, GBLD345, 0770, Tocris Bioscience

Citations for GBLD 345

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Currently there are no citations for GBLD 345.

Reviews for GBLD 345

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.