GBLD 345

Discontinued Product

Unfortunately GBLD 345 (Cat. No. 0770) has been withdrawn from sale for commercial reasons.
Cat.No. 0770 - GBLD 345 | C21H21N5O2 | CAS No. 122479-08-7
Description: High affinity benzodiazepine agonist
Chemical Name: 2-(4-Aminophenyl)-3-methoxy-6-(3-methoxyphenyl)-methylimidazo[1,2-b]pyridazine
Datasheet
Citations
Literature

Biological Activity

A high affinity benzodiazepine agonist (IC50 against diazepam = 1 nM).

Technical Data

M. Wt 375.43
Formula C21H21N5O2
Storage Store at RT
CAS Number 122479-08-7
Smiles NC(C=C4)=CC=C4C2=C(OC)N(C(C=C3)=N2)N=C3NCC1=CC=CC(OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 375.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.66 mL 13.32 mL 26.64 mL
5 mM 0.53 mL 2.66 mL 5.33 mL
10 mM 0.27 mL 1.33 mL 2.66 mL
50 mM 0.05 mL 0.27 mL 0.53 mL

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Reconstitution Calculator

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service.
Safety Datasheet

References

References are publications that support the products' biological activity.

Davies et al (1992) Substituted imidazo[1,2-b]pyridazines. New compounds with activity at central and peripheral benzodiazepine receptors. Biochem.Pharmacol. 44 1555 PMID: 1358075

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Citations for GBLD 345

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Pathways for GBLD 345

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