Discontinued Product

Flunitrazepam (Cat. No. 4047) has been withdrawn from sale for commercial reasons.
Description: Acts at the benzodiazepene modulatory site
Chemical Name: 5-(2-Fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
Purity: ≥99% (HPLC)
Literature (2)

Biological Activity for Flunitrazepam

Ligand at the GABAA receptor benzodiazepine modulatory site. Exhibits hypnotic effects; also displays anxiolytic and sedative properties.

Technical Data for Flunitrazepam

M. Wt 313.28
Formula C16H12FN3O3
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 1622-62-4
PubChem ID 3380
Smiles CN(C1=CC=C([N+]([O-])=O)C=C1C(C3=CC=CC=C3F)=NC2)C2=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Flunitrazepam

References for Flunitrazepam

References are publications that support the biological activity of the product.

Johnston et al (1998) Flunitrazepam rapidly reduces GABAA receptor subunit protein expression via a protein kinase C-dependent mechanism. Br.J.Pharmacol. 124 1338 PMID: 9723942

Merck Index 14 4146

Malanciuc et al (2009) Analytical characterization of flunitra. Farmacia 57 167

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Keywords: Flunitrazepam, Flunitrazepam supplier, hypnotic, benzodiazepine, gabaa, receptors, modulatory, binding, sites, agonists, GABAA, Receptors, 4047, Tocris Bioscience

Citations for Flunitrazepam

Citations are publications that use Tocris products.

Currently there are no citations for Flunitrazepam.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.