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Submit ReviewFlunitrazepam
Discontinued Product
Flunitrazepam (Cat. No. 4047) has been withdrawn from sale for commercial reasons.
Description: Acts at the benzodiazepene modulatory site
Chemical Name: 5-(2-Fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
Purity: ≥99% (HPLC)
Biological Activity for Flunitrazepam
Ligand at the GABAA receptor benzodiazepine modulatory site. Exhibits hypnotic effects; also displays anxiolytic and sedative properties.
Technical Data for Flunitrazepam
| M. Wt | 313.28 |
| Formula | C16H12FN3O3 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 1622-62-4 |
| PubChem ID | 3380 |
| InChI Key | PPTYJKAXVCCBDU-UHFFFAOYSA-N |
| Smiles | CN(C1=CC=C([N+]([O-])=O)C=C1C(C3=CC=CC=C3F)=NC2)C2=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Flunitrazepam
References for Flunitrazepam
References are publications that support the biological activity of the product.
Johnston et al (1998) Flunitrazepam rapidly reduces GABAA receptor subunit protein expression via a protein kinase C-dependent mechanism. Br.J.Pharmacol. 124 1338 PMID: 9723942
Merck Index 14 4146
Malanciuc et al (2009) Analytical characterization of flunitra. Farmacia 57 167
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Keywords: Flunitrazepam, Flunitrazepam supplier, hypnotic, benzodiazepine, gabaa, receptors, modulatory, binding, sites, agonists, GABAA, Receptors, 4047, Tocris Bioscience
Citations for Flunitrazepam
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Currently there are no citations for Flunitrazepam.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.