Flunitrazepam

Pricing Availability Delivery Time Qty
Cat.No. 4047 - Flunitrazepam | C16H12FN3O3 | CAS No. 1622-62-4
Description: Acts at the benzodiazepene modulatory site
Chemical Name: 5-(2-Fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Ligand at the GABAA receptor benzodiazepine modulatory site. Exhibits hypnotic effects; also displays anxiolytic and sedative properties.

Technical Data

M. Wt 313.28
Formula C16H12FN3O3
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 1622-62-4
PubChem ID 3380
InChI Key PPTYJKAXVCCBDU-UHFFFAOYSA-N
Smiles CN(C1=CC=C([N+]([O-])=O)C=C1C(C3=CC=CC=C3F)=NC2)C2=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 3.13 10

Preparing Stock Solutions

The following data is based on the product molecular weight 313.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.19 mL 15.96 mL 31.92 mL
5 mM 0.64 mL 3.19 mL 6.38 mL
10 mM 0.32 mL 1.6 mL 3.19 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Johnston et al (1998) Flunitrazepam rapidly reduces GABAA receptor subunit protein expression via a protein kinase C-dependent mechanism. Br.J.Pharmacol. 124 1338 PMID: 9723942

Merck Index 14 4146 PMID:

Malanciuc et al (2009) Analytical characterization of flunitrazepam. Farmacia 57 167 PMID:


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Keywords: Flunitrazepam, supplier, hypnotic, benzodiazepine, gabaa, receptors, modulatory, binding, sites, agonists, GABAA, Receptors, Tocris Bioscience

Citations for Flunitrazepam

Citations are publications that use Tocris products.

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Pathways for Flunitrazepam

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