Fluorescent false neurotransmitter (FFN). Targets neuronal vesicular monoamine transporter (VMAT) 2; inhibits serotonin binding to VMAT2 (IC50 = 1 μM). Excitation and emission maxima are 406 and 501 nm in pH 7 buffer, respectively.
Sold with the permission of Columbia University
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 284.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.25 mM||14.07 mL||70.34 mL||140.67 mL|
|1.25 mM||2.81 mL||14.07 mL||28.13 mL|
|2.5 mM||1.41 mL||7.03 mL||14.07 mL|
|12.5 mM||0.28 mL||1.41 mL||2.81 mL|
References are publications that support the biological activity of the product.
Gubernator et al (2009) Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science 324 1441 PMID: 19423778
Zhang et al (2009) Dopamine release at individual presynaptic terminals visualized with FFNs. J.Vis.Exp. 30 PMID: 19721412
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