FFN 511

Discontinued Product

FFN 511 (Cat. No. 3878) has been withdrawn from sale for commercial reasons.
Description: Fluorescent substrate for VMAT2
Chemical Name: 9-(2-Aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-[1]-benzopyrano[6,7,8-ij]quinolizin-11-one
Purity: ≥99% (HPLC)
Literature (1)

Biological Activity for FFN 511

FFN 511 is a fluorescent false neurotransmitter (FFN). Targets neuronal vesicular monoamine transporter (VMAT) 2; inhibits serotonin binding to VMAT2 (IC50 = 1 μM). Excitation and emission maxima are 406 and 501 nm in pH 7 buffer, respectively.

Licensing Information

Sold with the permission of Columbia University

Technical Data for FFN 511

M. Wt 284.35
Formula C17H20N2O2
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 1004548-96-2
PubChem ID 23725121
Smiles NCCC(C1=C(O4)C3=C2C(CCCN2CCC3)=C1)=CC4=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for FFN 511

Certificate of Analysis / Product Datasheet
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References for FFN 511

References are publications that support the biological activity of the product.

Gubernator et al (2009) Fluorescent false neurotransmitters visualize DA release from individual presynaptic terminals. Science 324 1441 PMID: 19423778

Zhang et al (2009) DA release at individual presynaptic terminals visualized with FFNs. J.Vis.Exp. 30 PMID: 19721412

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Citations for FFN 511

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Currently there are no citations for FFN 511.

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Literature in this Area

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

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