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FFN 206 dihydrochloride
Biological Activity for FFN 206 dihydrochloride
FFN 206 dihydrochloride is a fluorescent VMAT2 substrate (IC50 app = 1.15 μM). Allows detection of VMAT2 subcellular locations in cell culture. Exhibits no detectable inhibition of DAT. Excitation maximum = 369 nm; emission maximum = 464 nm.
Sold with the permission of Columbia University
Optical Data for FFN 206 dihydrochloride
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Technical Data for FFN 206 dihydrochloride
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for FFN 206 dihydrochloride
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for FFN 206 dihydrochloride
The following data is based on the product molecular weight 291.17. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.43 mL||17.17 mL||34.34 mL|
|5 mM||0.69 mL||3.43 mL||6.87 mL|
|10 mM||0.34 mL||1.72 mL||3.43 mL|
|50 mM||0.07 mL||0.34 mL||0.69 mL|
Product Datasheets for FFN 206 dihydrochloride
References for FFN 206 dihydrochloride
References are publications that support the biological activity of the product.
Hu et al (2013) New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2). ACS Chem.Biol. 8 1947 PMID: 23859623
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2 Citations for FFN 206 dihydrochloride
Citations are publications that use Tocris products. Selected citations for FFN 206 dihydrochloride include:
Hoffman et al (2018) Merkel cells activate sensory neural pathways through adrenergic synapses. Neuron 100 1401 PMID: 30415995
Simon C et al (2019) Drosophila Ptp4E regulates vesicular packaging for monoamine-neuropeptide co-transmission. J Cell Sci 132 PMID: 30837287
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Fluorescent Dyes and Probes Research Product Guide
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