Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewFFN 206 dihydrochloride
Description: Fluorescent VMAT2 substrate
Chemical Name: 4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride
Purity: ≥99% (HPLC)
Biological Activity
Fluorescent VMAT2 substrate (IC50 app = 1.15 μM). Allows detection of VMAT2 subcellular locations in cell culture. Exhibits no detectable inhibition of DAT. Excitation maximum = 369 nm; emission maximum = 464 nm.
Licensing Information
Sold with the permission of Columbia University
Optical Data for FFN 206 dihydrochloride
| λabs | 369 nm |
|---|---|
| λem | 464 nm |
Technical Data
| M. Wt | 291.17 |
| Formula | C12H14N2O2.2HCl |
| Storage | Store at -20°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 1883548-88-6 |
| PubChem ID | 91826079 |
| InChI Key | ODENAPXTSFPACZ-UHFFFAOYSA-N |
| Smiles | CNC1=CC=C2C(OC(C=C2CCN)=O)=C1.Cl.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 29.12 | 100 | |
| DMSO | 14.56 | 50 |
Preparing Stock Solutions
The following data is based on the product molecular weight 291.17. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.43 mL | 17.17 mL | 34.34 mL |
| 5 mM | 0.69 mL | 3.43 mL | 6.87 mL |
| 10 mM | 0.34 mL | 1.72 mL | 3.43 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.69 mL |
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
Product Datasheets
References
References are publications that support the biological activity of the product.
Hu et al (2013) New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2). ACS Chem.Biol. 8 1947 PMID: 23859623
If you know of a relevant reference for FFN 206 dihydrochloride, please let us know.
View Related Products by Target
Keywords: FFN 206 dihydrochloride, FFN 206 dihydrochloride supplier, FFN206, dihydrochloride, Fluorescent, VMAT2, substrates, vesicular, monoamine, transporters, Vesicular, Monoamine, Transporters, Substrates, 5043, Tocris Bioscience
1 Citation for FFN 206 dihydrochloride
Citations are publications that use Tocris products. Selected citations for FFN 206 dihydrochloride include:
Hoffman et al (2018) Merkel cells activate sensory neural pathways through adrenergic synapses. Neuron 100 1401 PMID: 30415995
Do you know of a great paper that uses FFN 206 dihydrochloride from Tocris? Please let us know.
Reviews for FFN 206 dihydrochloride
There are currently no reviews for this product. Be the first to review FFN 206 dihydrochloride and earn rewards!
Have you used FFN 206 dihydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide [Spring/Summer 2019]New
Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.
- 7-TM Receptors
- Enzymes
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Transporters
- Chemogenetics
- Epigenetics
- Fluorescent Imaging
- PROTACs
- Signal Transduction
- Stem Cells