FFN 200 dihydrochloride

Pricing Availability Delivery Time Qty
Cat.No. 5911 - FFN 200 dihydrochloride | C11H14Cl2N2O2
Description: Selective fluorescent VMAT2 substrate
Chemical Name: 4-(2-Aminoethyl)-7-amino-2H-1-benzopyran-2-one dihydrochloride
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Selective fluorescent VMAT2 substrate. Selectively traces exocytosis in dopaminergic neuronal cell culture and brain tissue. Excitation and emission maxima are 352 and 451 nm, respectively.

Licensing Information

Sold with the permission of Columbia University.

FFN200 in Cultured Dopamine Neurons

FFN200 in vesicle clusters in axons of cultured dopaminergic neurons, and exocytosis upon high potassium stimulation (time lapse acquisition at 12 images/min).

Technical Data

M. Wt 277.15
Formula C11H14Cl2N2O2
Storage Store at -20°C
Purity ≥98% (HPLC)
PubChem ID 124201850
InChI Key YNQXRSNAOWBGLD-UHFFFAOYSA-N
Smiles NC1=CC(OC(C=C2CCN)=O)=C2C=C1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 27.71 100
water 27.71 100

Preparing Stock Solutions

The following data is based on the product molecular weight 277.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.61 mL 18.04 mL 36.08 mL
5 mM 0.72 mL 3.61 mL 7.22 mL
10 mM 0.36 mL 1.8 mL 3.61 mL
50 mM 0.07 mL 0.36 mL 0.72 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Pereira et al (2015) Fluorescent false neurotransmitter reveals functionally silent dopamine vesicle clusters in the striatum. Nat.Neurosci. 19 578 PMID: 26900925

Li (2017) Probes for monitoring regulated exocytosis. Cell Calcium 64 65 PMID: 28089267


If you know of a relevant reference for FFN 200 dihydrochloride, please let us know.

Keywords: FFN 200 dihydrochloride, supplier, FFN200, dihydrochloride, fluorescent, false, neurotransmitters, VMAT2, vesicular, monoamine, transporters, 2, dopaminergic, substrates, Fluorescent, Probes, Vesicular, Monoamine, Transporters, Fluorescent, Probes, Tocris Bioscience

Citations for FFN 200 dihydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for FFN 200 dihydrochloride. Do you know of a great paper that uses FFN 200 dihydrochloride from Tocris? If so please let us know.

Reviews for FFN 200 dihydrochloride

There are currently no reviews for this product. Be the first to review FFN 200 dihydrochloride and earn rewards!

Have you used FFN 200 dihydrochloride?

Submit a review and receive an Amazon gift card.

$10US/$10CAN/€7/£6 gift card for a review without an image

$25US/$25CAN/€18/£15 gift card for a review with an image

*Offer only valid in the USA / Canada, UK and Europe

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


New Product Guide

New Product Guide (Spring/Summer 2018)

Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Aptamers
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells