You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Discontinued ProductEnterostatin (Cat. No. 3612) has been withdrawn from sale for commercial reasons.
N' terminal peptide fragment of procolipase that binds to the β-subunit of F1-ATPase. Activates the ERK and cAMP signaling pathways, and downregulates expression of Krüppel-like factor 4 (KLF4) and agouti-related peptide (AgRP) in vitro. Inhibits insulin secretion from pancreatic β-cells by downregulating expression of dynamin2 and altering protein trafficking. Reduces dietary fat intake via activation of CCK1, induces satiety, enhances memory-consolidation and exhibits hypocholesterolemic activity in vivo. Orally active.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Takenaka et al (2008) Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides 29 2175 PMID: 18824202
Park et al (2009) Enterostatin affects cyclic AMP and ERK signaling pathways to regulate Agouti-related Protein (AgRP) expression. Peptides 30 181 PMID: 19059445
Park et al (2009) Enterostatin alters protein trafficking to inhibit Ins secretion in Beta-TC6 cells. Peptides 30 1866 PMID: 19563849
View Related Products by Target
Keywords: Enterostatin, Enterostatin supplier, Binds, β-subunit, beta-subunit, F1-ATPase, anorexigenic, peptide, activators, CCK1, reduces, dietary, fat, intake, P-Type, ATPase, V-Type, E-Type, F-Type, ATPases, GTPases, Oxidative, phosphorylation, Cholecystokinin1, Receptors, CCK, Cholecystokinin, H+-ATPase, Receptor, Phosphorylation, 3612, Tocris Bioscience
Citations for Enterostatin
Citations are publications that use Tocris products.
Currently there are no citations for Enterostatin.
Reviews for Enterostatin
There are currently no reviews for this product. Be the first to review Enterostatin and earn rewards!
Have you used Enterostatin?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image