Novel group I/group II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG (Cat. No. 0336).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 100 mM in 1.1eq. NaOH|
Preparing Stock Solutions
The following data is based on the product molecular weight 223.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.48 mL||22.4 mL||44.8 mL|
|5 mM||0.9 mL||4.48 mL||8.96 mL|
|10 mM||0.45 mL||2.24 mL||4.48 mL|
|50 mM||0.09 mL||0.45 mL||0.9 mL|
References are publications that support the products' biological activity.
Bedingfield et al (1995) Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs). Br.J.Pharmacol. 116 3323 PMID: 8719814
Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493 PMID: 8730745
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Keywords: E4CPG, supplier, Group, II, group, I, mGlur, antagonists, Receptors, mGlu2, mGlu3, mGluR2, mGluR3, Glutamate, Metabotropic, mGlu1, mGlu5, mGluR1, mGluR5, Glutamate, (Metabotropic), Group, I, Receptors, Glutamate, (Metabotropic), Group, II, Receptors, Glutamate, (Metabotropic), Group, I, Receptors, Tocris Bioscience
1 Citation for E4CPG
Citations are publications that use Tocris products. Selected citations for E4CPG include:
Newman (2005) Calcium increases in retinal glial cells evoked by light-induced neuronal activity. Neuropharmacology 25 5502 PMID: 15944378
Do you know of a great paper that uses E4CPG from Tocris? If so please let us know.
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