Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewHigh affinity, cell-permeable inhibitor of casein kinase 2 (CK2) (Ki = 40 nM; IC50 = 0.13 μM). Displays no activity at CK1 at concentrations up to 200 μM. Also inhibits Pim kinase (IC50 values are 0.097, 0.148 and 1.6 μM for Pim-3, Pim-1 and Pim-2 kinase respectively), and protein kinase D1 (IC50 = 0.18 μM). Derivative of TBB (Cat.No. 2275).
M. Wt | 476.79 |
Formula | C9H7Br4N3 |
Storage | Store at +4°C |
Purity | ≥99% (HPLC) |
Smiles | BrC1=C(Br)C(Br)=C(NC(N(C)C)=N2)C2=C1Br |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Inglis et al (2008) Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system. J.Biol.Chem. 284 2598 PMID: 19004816
Pagano et al (2008) The selectivity of inhibitors of protein kinase CK2: an update. Biochem.J. 415 353 PMID: 18588507
Pagano et al (2004) 2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2. Biochem.Biophys.Res.Comm. 321 1040
Keywords: DMAT, DMAT supplier, cell-permeable, kinase, inhibitors, inhibits, casein, 2, CK2, pim, pim1, pim2, pim3, protein, d1, pkd1, Casein, Kinase, Pim, Protein, D, 3686, Tocris Bioscience
Citations are publications that use Tocris products.
Currently there are no citations for DMAT.
There are currently no reviews for this product. Be the first to review DMAT and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
This product guide provides a review of the cell cycle and DNA damage research area and lists over 170 products, including research tools for: