(±)-CPSI 1306

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Cat.No. 4400 - (±)-CPSI 1306 | C15H16F2N2O3 | CAS No. 1309793-47-2
Description: Reported macrophage migration inhibitory factor (MIF) inhibitor
Chemical Name: 2-[3-(3-(2,4-Difluorophenyl)-4,5-dihydro-5-isoxazolyl]-1-(4-morpholinyl)ethanone
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Reported to be a macrophage inhibitory factor (MIF) inhibitor.

Compound Libraries

(±)-CPSI 1306 is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 310.3
Formula C15H16F2N2O3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1309793-47-2
PubChem ID 59723793
InChI Key GUWOSEVHCSNYFK-UHFFFAOYSA-N
Smiles FC(C=C2F)=CC=C2C1=NOC(CC(N3CCOCC3)=O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.03 100
ethanol 3.1 10

Preparing Stock Solutions

The following data is based on the product molecular weight 310.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.22 mL 16.11 mL 32.23 mL
5 mM 0.64 mL 3.22 mL 6.45 mL
10 mM 0.32 mL 1.61 mL 3.22 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Kithcart et al (2010) A small-molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease. FASEB J. 24 4459 PMID: 20624927

Sanchez-Zamora et al (2010) Macrophage migration inhibitory factor is a therapeutic target in treatment of non-insulin-dependent diabetes mellitus. FASEB J. 24 2583 PMID: 20203087


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Citations for (±)-CPSI 1306

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Literature in this Area

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Pathways for (±)-CPSI 1306

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