(±)-CPSI 1306

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Description: Reported macrophage migration inhibitory factor (MIF) inhibitor
Chemical Name: 2-[3-(3-(2,4-Difluorophenyl)-4,5-dihydro-5-isoxazolyl]-1-(4-morpholinyl)ethanone
Purity: ≥98% (HPLC)
Literature (1)

Biological Activity for (±)-CPSI 1306

(±)-CPSI 1306 is reported to be a macrophage inhibitory factor (MIF) inhibitor.

This product is racemic.

Compound Libraries for (±)-CPSI 1306

(±)-CPSI 1306 is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Antiviral Library. Find out more about compound libraries available from Tocris.

Technical Data for (±)-CPSI 1306

M. Wt 310.3
Formula C15H16F2N2O3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1309793-47-2
PubChem ID 59723793
Smiles FC(C=C2F)=CC=C2C1=NOC(CC(N3CCOCC3)=O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for (±)-CPSI 1306

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 31.03 100
ethanol 3.1 10

Preparing Stock Solutions for (±)-CPSI 1306

The following data is based on the product molecular weight 310.3. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.22 mL 16.11 mL 32.23 mL
5 mM 0.64 mL 3.22 mL 6.45 mL
10 mM 0.32 mL 1.61 mL 3.22 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

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Product Datasheets for (±)-CPSI 1306

References for (±)-CPSI 1306

References are publications that support the biological activity of the product.

Kithcart et al (2010) A small-molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease. FASEB J. 24 4459 PMID: 20624927

Sanchez-Zamora et al (2010) Macrophage migration inhibitory factor is a therapeutic target in treatment of non-Ins-dependent diabetes mellitus. FASEB J. 24 2583 PMID: 20203087

If you know of a relevant reference for (±)-CPSI 1306, please let us know.

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Citations for (±)-CPSI 1306

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Literature in this Area

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