Selective, high affinity P2Y12 receptor antagonist (pKi = 6.9 for hP2Y12 receptor). Inhibits ADP-induced platelet aggregation; potent antithrombotic agent. Requires bioactivation, unlike PSB 0739 (Cat. No. 3983). (+)-Clopidogrel hydrogen sulfate (Cat. No. 1820) also available.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 358.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.79 mL||13.96 mL||27.91 mL|
|5 mM||0.56 mL||2.79 mL||5.58 mL|
|10 mM||0.28 mL||1.4 mL||2.79 mL|
|50 mM||0.06 mL||0.28 mL||0.56 mL|
References are publications that support the products' biological activity.
Kugelgen (2006) Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 110 415 PMID: 16257449
If you know of a relevant reference for (±)-Clopidogrel hydrochloride, please let us know.
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Keywords: (±)-Clopidogrel hydrochloride, supplier, Selective, P2Y12, antagonists, Receptors, Purinergic, purinoceptors, p2yt, Plavix, Purinergic, P2Y, Receptors, Purinergic, P2Y, Receptors, Tocris Bioscience
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