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Cat.No. 5825 - CHAPSO | C32H58N2O8S | CAS No. 82473-24-3
Description: Zwitterionic detergent
Chemical Name: 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate

Biological Activity

A zwitterionic nondenaturing detergent for solubilizing membrane proteins.

Technical Data

M. Wt 630.88
Formula C32H58N2O8S
Storage Store at RT
CAS Number 82473-24-3
PubChem ID 50987331
Smiles O[C@@H]1CC[C@@]2(C)[C@@](C[C@@H](O)C3[C@@]([H])2C[C@H](O)[C@@]4(C)[C@]([H])3CC[C@@]([H])4[C@]([H])(C)CCC(NCCC[N+](C)(C)CC(O)CS([O-])(=O)=O)=O)([H])C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
water 63.09 100
DMSO 63.09 100

Preparing Stock Solutions

The following data is based on the product molecular weight 630.88. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.59 mL 7.93 mL 15.85 mL
5 mM 0.32 mL 1.59 mL 3.17 mL
10 mM 0.16 mL 0.79 mL 1.59 mL
50 mM 0.03 mL 0.16 mL 0.32 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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References are publications that support the biological activity of the product.

Cladera et al (1997) Liposome solubilization and membrane protein reconstitution using Chaps and Chapso. Eur.J.Biochem. 243 798 PMID: 9057848

Zhao et al (2014) Detergent-dependent separation of postsynaptic density, membrane rafts and other subsynaptic structures from the synaptic plasma membrane of rat forebrain. J.Neurochem. 131 147 PMID: 24985044

If you know of a relevant reference for CHAPSO, please let us know.

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Keywords: CHAPSO, CHAPSO supplier, zwitterionic, detergents, solubilizes, solubilizing, membrane, proteins, Biochemicals, and, Molecular, Biology, 5825, Tocris Bioscience

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