CHAPS

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Cat.No. 3172 - CHAPS | C32H58N2O7S | CAS No. 75621-03-3
Description: Zwitterionic detergent
Chemical Name: 3-[(3-Cholamidopropyl)-dimethylammonio]-1-propanesulfonate
Purity: ≥98%
Datasheet
Citations
Literature

Biological Activity

CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins.

Technical Data

M. Wt 614.88
Formula C32H58N2O7S
Storage Store at RT
Purity ≥98%
CAS Number 75621-03-3
PubChem ID 90488808
InChI Key UMCMPZBLKLEWAF-OHJCWZKSSA-N
Smiles O[C@@H]1CC[C@@]2(C)[C@@](C[C@@H](O)C3[C@@]([H])2C[C@H](O)[C@@]4(C)[C@]([H])3CCC4[C@]([H])(C)CCC(NCCC[N+](C)(C)CCCS([O-])(=O)=O)=O)([H])C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 614.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.63 mL 8.13 mL 16.26 mL
5 mM 0.33 mL 1.63 mL 3.25 mL
10 mM 0.16 mL 0.81 mL 1.63 mL
50 mM 0.03 mL 0.16 mL 0.33 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Pasquali et al (1997) Preparative two-dimensional gel electrophoresis of membrane proteins. Electrophoresis 18 2573 PMID: 9527487

Banerjee et al (1995) Differential solubilization of lipids along with membrane proteins by different classes of detergents. Chem.Phys.Lipids 77 65 PMID: 7586093


If you know of a relevant reference for CHAPS, please let us know.

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Keywords: CHAPS, supplier, Zwitterionic, detergent, Reagents, Biochemicals, and, Molecular, Biology, Tocris Bioscience

Citations for CHAPS

Citations are publications that use Tocris products.

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Literature in this Area

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New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

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Pathways for CHAPS

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