You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
cGMP Dependent Kinase Inhibitor Peptide
Discontinued ProductcGMP Dependent Kinase Inhibitor Peptide (Cat. No. 1883) has been withdrawn from sale for commercial reasons.
cGMP Dependent Kinase Inhibitor Peptide is a competitive inhibitor of cGMP-dependent protein kinase (PKG); analog of a substrate peptide corresponding to a phosphorylation site of histone H2B. Competes with synthetic substrates (Ki = 86 mM) but does not inhibit phosphorylation of intact histones by PKG. Inhibits phosphorylation of intact histones by PKA.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Bhatnagar et al (1988) Synthetic peptide analogues differentially alter the binding affinities of cyclic nucleotide dependent protein kinases for nucleotide substrates. Biochemistry 27 1988 PMID: 2837278
Glass (1983) Differential responses of cyclic GMP-dependent and cyclic AMP-dependent protein kinases to synthetic peptide inhibitors. Biochem.J. 213 159 PMID: 6615418
Glass et al (1986) Differential and common recognition of the catalytic sites of the cGMP-dependent and cAMP-dependent protein kinases by inhibitory peptides derived from the heat-stable inhibitor protein. J.Biol.Chem. 261 12166 PMID: 3017964
View Related Products by Target
View Related Products by Product Action
Keywords: cGMP dependent kinase inhibitor peptide, cGMP dependent kinase inhibitor peptide supplier, inhibitors, inhibits, protein, kinases, A, G, PKA, PKG, [Ala32]H2B(29-35), Protein, Kinase, 1883, Tocris Bioscience
Citations for cGMP Dependent Kinase Inhibitor Peptide
Citations are publications that use Tocris products.
Currently there are no citations for cGMP Dependent Kinase Inhibitor Peptide.
Reviews for cGMP Dependent Kinase Inhibitor Peptide
Average Rating: 5 (Based on 1 Review.)
Have you used cGMP Dependent Kinase Inhibitor Peptide?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
We examined the regulatory mechanism of the PKG holoenzymes. The development of cGMP-independent peptide activators of PKG I alpha, derived from this helical segment was found bridging the regulatory and catalytic domains.
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.