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Biological Activity for CD 1530
CD 1530 is a potent and selective RARγ receptor agonist (Ki values are 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively). Activates transcriptional activity (AC50 = 1.8 nM).
Compound Libraries for CD 1530
Technical Data for CD 1530
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for CD 1530
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for CD 1530
The following data is based on the product molecular weight 398.49. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.51 mL||12.55 mL||25.09 mL|
|5 mM||0.5 mL||2.51 mL||5.02 mL|
|10 mM||0.25 mL||1.25 mL||2.51 mL|
|50 mM||0.05 mL||0.25 mL||0.5 mL|
References for CD 1530
References are publications that support the biological activity of the product.
Thacher et al (2000) Therapeutic applications for ligands of retinoid receptors. Curr.Pharmaceut.Des. 6 25
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Keywords: CD 1530, CD 1530 supplier, Potent, selective, RARγ, RARgamma, agonists, RAMBA, Retinoic, Acid, Receptors, CD1530, 2554, Tocris Bioscience
3 Citations for CD 1530
Citations are publications that use Tocris products. Selected citations for CD 1530 include:
Duprey-Díaz et al (2016) Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System afterOptic Nerve Injury PLoS One 11 e0162626 PMID: 27611191
Garnaas et al (2012) Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol 372 178 PMID: 22982668
Nguyen et al (2017) Retinoic acid receptor regulation of epimorphic and homeostatic regeneration in the axolotl. Development 144 601 PMID: 28087637
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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