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The Retinoid Receptors Scientific Review is part of the range of scientific reviews and bulletins produced by Tocris and written by leading experts summarizing the most recent developments in research and available products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Alexander R. Moise, University of Kansas
Review excerpt: "Retinoid signaling can induce cellular differentiation or apoptosis, which is partly relevant in the treatment of cancer. Due to this, there has been a tremendous effort to develop safe and receptor-selective compounds. Structural analysis of various receptors in combination with ATRA, 9-cis-RA or synthetic agonists or antagonists has provided the retinoid field with an unprecedented molecular understanding of the subtle changes necessary to produce the desired receptor response and to confer specific activity."