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Discontinued ProductBromodechloroambenonium dibromide (Cat. No. 0422) has been withdrawn from sale for commercial reasons.
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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Lands et al (1958) An investigation of the structure-activity correlations within a series of amben. analogs. J.Pharmacol.Exp.Ther. 123 121 PMID: 13550066
Webb (1965) Affinity for benzoquinonium, and amben. derivatives for the acetylcholine receptor, tested on the electroplax, and for acetylcholinesterase in solution. Biochim.Biophys.Acta 102 172 PMID: 5833399
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Literature in this Area
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Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.