Discontinued ProductUnfortunately Bromodechloroambenonium dibromide (Cat. No. 0422) has been withdrawn from sale for commercial reasons.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 786.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.27 mL||6.36 mL||12.72 mL|
|5 mM||0.25 mL||1.27 mL||2.54 mL|
|10 mM||0.13 mL||0.64 mL||1.27 mL|
|50 mM||0.03 mL||0.13 mL||0.25 mL|
References are publications that support the products' biological activity.
Lands et al (1958) An investigation of the structure-activity correlations within a series of ambenonium analogs. J.Pharmacol.Exp.Ther. 123 121 PMID: 13550066
Webb (1965) Affinity for benzoquinonium, and ambenonium derivatives for the acetylcholine receptor, tested on the electroplax, and for acetylcholinesterase in solution. Biochim.Biophys.Acta 102 172 PMID: 5833399
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Keywords: Bromodechloroambenonium dibromide, supplier, WIN-13, 357, Other, Acetylcholine, Non-selective, Muscarinics, Cholinesterases, Other, Acetylcholine, Tocris Bioscience
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Currently there are no citations for Bromodechloroambenonium dibromide.
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Literature in this Area
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Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.