BRL 52537 hydrochloride
The most κ/μ-selective and among the most potent κ ligands known (25 times more potent than morphine in vivo).
Sold with the permission of GlaxoSmithKline
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|water||1.96||5mM with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 391.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.55 mL||12.76 mL||25.53 mL|
|5 mM||0.51 mL||2.55 mL||5.11 mL|
|10 mM||0.26 mL||1.28 mL||2.55 mL|
|50 mM||0.05 mL||0.26 mL||0.51 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Vecchietti et al (1991) (2S)-1-(Arylacetyl)-2-(aminomethyl)piperidine derivatives: novel, highly selective κ opioid analgesics. J.Med.Chem. 34 397 PMID: 1846921
If you know of a relevant reference for BRL 52537 hydrochloride, please let us know.
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Keywords: Potent selective κ-opioid kappa-opioid agonist agonists KOP Receptors OP2 BRL52537 hydrochloride GlaxoSmithKline GSK Kappa Opioid Receptors
Citations for BRL 52537 hydrochloride
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