BRD 7116

Discontinued Product

BRD 7116 (Cat. No. 5336) has been withdrawn from sale for commercial reasons.
Description: Inhibitor of leukemia stem cell activity
Chemical Name: N,N'-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]
Purity: ≥98% (HPLC)
Literature (5)

Biological Activity for BRD 7116

Inhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM). Exhibits >100-fold selectivity for LSCs over normal hematopoietic stem cells.

Technical Data for BRD 7116

M. Wt 496.66
Formula C28H36N2O4S
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 329059-55-4
PubChem ID 981129
Smiles O=C(C1C(C)(C)C1(C)C)NC(C=C2)=CC=C2S(C3=CC=C(NC(C4C(C)(C)C4(C)C)=O)C=C3)(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for BRD 7116

References are publications that support the biological activity of the product.

Hartwell et al (2013) Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nat.Chem.Biol. 9 840 PMID: 24161946

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Keywords: BRD 7116, BRD 7116 supplier, BRD7116, leukemia, stem, cells, inhibitors, inhibits, LSCs, Cancer, Stem, Cells, 5336, Tocris Bioscience

Citations for BRD 7116

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Currently there are no citations for BRD 7116.

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Literature in this Area

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