BIS-TRIS

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Cat.No. 5216 - BIS-TRIS | C8H19NO5 | CAS No. 6976-37-0
Description: Commonly used buffering agent
Chemical Name: Bis-(2-hydroxyethyl)aminotris(hydroxymethyl)methane
Purity: ≥99%
Datasheet
Citations (1)
Literature

Biological Activity

Commonly used buffering agent.

Technical Data

M. Wt 209.24
Formula C8H19NO5
Storage Store at RT
Purity ≥99%
CAS Number 6976-37-0
PubChem ID 81462
InChI Key OWMVSZAMULFTJU-UHFFFAOYSA-N
Smiles OCC(CO)(CO)N(CCO)CCO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 418.48 2000

Preparing Stock Solutions

The following data is based on the product molecular weight 209.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.78 mL 23.9 mL 47.79 mL
5 mM 0.96 mL 4.78 mL 9.56 mL
10 mM 0.48 mL 2.39 mL 4.78 mL
50 mM 0.1 mL 0.48 mL 0.96 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

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1 Citation for BIS-TRIS

Citations are publications that use Tocris products. Selected citations for BIS-TRIS include:

Cassé et al (2012) Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals. J Neurosci 32 5186 PMID: 22496564


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