Orally active antihypertensive agent which displays a wide range of activities in vitro and in vivo. Inhibits L-, N- and T-type Ca2+ channels. Also inhibits aldosterone-induced mineralocorticoid receptor activation. Exhibits cardioprotective and antiartherosclerotic effects.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 542.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.75 mM||2.46 mL||12.3 mL||24.6 mL|
|3.75 mM||0.49 mL||2.46 mL||4.92 mL|
|7.5 mM||0.25 mL||1.23 mL||2.46 mL|
|37.5 mM||0.05 mL||0.25 mL||0.49 mL|
References are publications that support the biological activity of the product.
Yao et al (2006) Pharmacological, pharmacokinetic, and clinical properties of benidipine hydrochloride, a novel long-acting calcium channel blocker. J.Pharmacol.Sci. 100 243 PMID: 16565579
Kosaka et al (2010) The L-, N-, T-type triple calcium channel blocker benidipine acts as an antagonist of mineralocorticoid receptor, a member of nuclear receptor family. Eur.J.Pharmacol. 635 49 PMID: 20307534
If you know of a relevant reference for Benidipine hydrochloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Benidipine hydrochloride, Benidipine hydrochloride supplier, L-type, T-type, N-type, calcium, channels, Ca2+, blockers, inhibitors, inhibits, selective, voltage-gated, voltage-dependent, CaV, mineralocorticoid, receptor, antagonist, KW3049, KW, 3049, Non-selective, Cav, Channels, Mineralocorticoid, Receptor, 3934, Tocris Bioscience
Citations for Benidipine hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for Benidipine hydrochloride. Do you know of a great paper that uses Benidipine hydrochloride from Tocris? Please let us know.
Reviews for Benidipine hydrochloride
There are currently no reviews for this product. Be the first to review Benidipine hydrochloride and earn rewards!
Have you used Benidipine hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Fall/Winter 2018/2019)New
Our new product guide highlights over 190 new products added to the Tocris Bioscience range during the second half of 2018.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells