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Discontinued ProductBenidipine hydrochloride (Cat. No. 3934) has been withdrawn from sale for commercial reasons.
Biological Activity for Benidipine hydrochloride
Orally active antihypertensive agent which displays a wide range of activities in vitro and in vivo. Inhibits L-, N- and T-type Ca2+ channels. Also inhibits aldosterone-induced mineralocorticoid receptor activation. Exhibits cardioprotective and antiartherosclerotic effects.
Technical Data for Benidipine hydrochloride
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Benidipine hydrochloride
References for Benidipine hydrochloride
References are publications that support the biological activity of the product.
Yao et al (2006) Pharmacological, pharmacokinetic, and clinical properties of benidipine hydrochloride, a novel long-acting calcium channel blocker. J.Pharmacol.Sci. 100 243 PMID: 16565579
Kosaka et al (2010) The L-, N-, T-type triple calcium channel blocker benidipine acts as an antagonist of mineralocorticoid receptor, a member of nuclear receptor family. Eur.J.Pharmacol. 635 49 PMID: 20307534
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Keywords: Benidipine hydrochloride, Benidipine hydrochloride supplier, L-type, T-type, N-type, calcium, channels, Ca2+, blockers, inhibitors, inhibits, selective, voltage-gated, voltage-dependent, CaV, mineralocorticoid, receptor, antagonist, KW3049, KW, 3049, Non-selective, Cav, Channels, Mineralocorticoid, Receptor, 3934, Tocris Bioscience
1 Citation for Benidipine hydrochloride
Citations are publications that use Tocris products. Selected citations for Benidipine hydrochloride include:
Bhandage et al (2019) Toxoplasma-Induced Hypermigration of Primary Cortical Microglia Implicates GABAergic Signaling. Front Cell Infect Microbiol 9 73 PMID: 30949457
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