β-CCB

Discontinued Product

0405 has been discontinued.

View all GABA<sub>A</sub> Receptors products.
Description: Benzodiazepine inverse agonist; putative endogenous ligand
Chemical Name: Butyl β-carboline-3-carboxylate
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity for β-CCB

An endogenous proconvulsant and anxiogenic benzodiazepine receptor ligand.

Technical Data for β-CCB

M. Wt 268.31
Formula C16H16N2O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 84454-35-3
PubChem ID 128618
InChI Key WGNGIELOOKACSB-UHFFFAOYSA-N
Smiles CCCCOC(=O)C1=CC2=C(NC3=C2C=CC=C3)C=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for β-CCB

References are publications that support the biological activity of the product.

Izquierdo (1989) A game with shifting mirrors. TiPS 10 473 PMID: 2575813

Pena et al (1986) Isolation and identification in bovine cerebral cortex of n-butyl β-carboline-3-carboxylate, a potent benzodiazepine binding inhibitor. Proc.Natl.Acad.Sci.U.S.A. 83 4952 PMID: 3014522

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Keywords: beta-CCB, beta-CCB supplier, Benzodiazepine, inverse, agonists, putative, endogenous, ligand, GABAA, Receptors, β-CCB, beta-CCB, 0405, Tocris Bioscience

Citations for β-CCB

Citations are publications that use Tocris products.

Currently there are no citations for β-CCB.

Reviews for β-CCB

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.