Arvanil

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Cat.No. 1354 - Arvanil | C28H41NO3 | CAS No. 128007-31-8
Description: Potent CB1 agonist; also anandamide transport inhibitor and TRPV1 agonist
Chemical Name: N-[(4-Hydroxy-3-methoxyphenyl)methyl]-5Z,8Z,11Z,14Z-eicosatetraenamide
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Cannabinoid CB1 and vanilloid TRPV1 (VR1) agonist (Ki values are 0.5 and 0.3 μM respectively). Also inhibits the anandamide transporter (IC50 = 3.6 μM). Analgesic, vasodilatory and anti-inflammatory in vivo.

Technical Data

M. Wt 439.64
Formula C28H41NO3
Storage Desiccate at -20°C
Purity ≥98% (HPLC)
CAS Number 128007-31-8
PubChem ID 6449767
InChI Key QVLMCRFQGHWOPM-ZKWNWVNESA-N
Smiles O=C(NCC1=CC=C(O)C(OC)=C1)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Di Marzo et al (2000) Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide. Eur.J.Pharmacol. 406 363 PMID: 11040343

Melck et al (1999) Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 receptors. Biochem.Biophys.Res.Commun. 262 275 PMID: 10448105

Szallasi and Di Marzo (2000) New perspectives on enigmatic vanilloid receptors. Trends Neurosci. 23 491 PMID: 11006466


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Citations for Arvanil

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