Discontinued Product

Arvanil (Cat. No. 1354) has been withdrawn from sale for commercial reasons.
Description: Potent CB1 agonist; also anandamide transport inhibitor and TRPV1 agonist
Chemical Name: N-[(4-Hydroxy-3-methoxyphenyl)methyl]-5Z,8Z,11Z,14Z-eicosatetraenamide
Purity: ≥98% (HPLC)
Literature (2)

Biological Activity for Arvanil

Arvanil is a cannabinoid CB1 and vanilloid TRPV1 (VR1) agonist (Ki values are 0.5 and 0.3 μM respectively). Also inhibits the anandamide transporter (IC50 = 3.6 μM). Analgesic, vasodilatory and anti-inflammatory in vivo.

Technical Data for Arvanil

M. Wt 439.64
Formula C28H41NO3
Storage Desiccate at -20°C
Purity ≥98% (HPLC)
CAS Number 128007-31-8
PubChem ID 6449767

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Arvanil

Certificate of Analysis / Product Datasheet
Select another batch:

References for Arvanil

References are publications that support the biological activity of the product.

Di Marzo et al (2000) Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide. Eur.J.Pharmacol. 406 363 PMID: 11040343

Melck et al (1999) Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 receptors. Biochem.Biophys.Res.Commun. 262 275 PMID: 10448105

Szallasi and Di Marzo (2000) New perspectives on enigmatic vanilloid receptors. Trends Neurosci. 23 491 PMID: 11006466

View Related Products by Product Action

View all CB1 Receptor Agonists

Keywords: Arvanil, Arvanil supplier, Potent, CB1, TRPV1, VR1, agonists, anandamide, transporters, inhibitors, inhibits, AMT, Cannabinoids, Monoamine, Neurotransmitter, Receptors, Vanillioid, TRPV, TRP, Channels, Transient, Receptor, Potential, cb1r, Cannabinoid, Transporters, 1354, Tocris Bioscience

Citations for Arvanil

Citations are publications that use Tocris products.

Currently there are no citations for Arvanil.

Reviews for Arvanil

There are currently no reviews for this product. Be the first to review Arvanil and earn rewards!

Have you used Arvanil?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cannabinoid Receptor Ligands Scientific Review

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.