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Biological Activity for Arvanil
Arvanil is a cannabinoid CB1 and vanilloid TRPV1 (VR1) agonist (Ki values are 0.5 and 0.3 μM respectively). Also inhibits the anandamide transporter (IC50 = 3.6 μM). Analgesic, vasodilatory and anti-inflammatory in vivo.
Technical Data for Arvanil
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for Arvanil
References are publications that support the biological activity of the product.
Di Marzo et al (2000) Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide. Eur.J.Pharmacol. 406 363 PMID: 11040343
Melck et al (1999) Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 receptors. Biochem.Biophys.Res.Commun. 262 275 PMID: 10448105
Szallasi and Di Marzo (2000) New perspectives on enigmatic vanilloid receptors. Trends Neurosci. 23 491 PMID: 11006466
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Keywords: Arvanil, Arvanil supplier, Potent, CB1, TRPV1, VR1, agonists, anandamide, transporters, inhibitors, inhibits, AMT, Cannabinoids, Monoamine, Neurotransmitter, Receptors, Vanillioid, TRPV, TRP, Channels, Transient, Receptor, Potential, cb1r, Cannabinoid, Transporters, 1354, Tocris Bioscience
Citations for Arvanil
Citations are publications that use Tocris products.
Currently there are no citations for Arvanil.
Reviews for Arvanil
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.