Angiotensin I (human, mouse, rat)

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Description: Endogenous precursor to angiotensin II (Cat. No. 1158)
Purity: ≥95% (HPLC)

Biological Activity for Angiotensin I (human, mouse, rat)

Angiotensin I (human, mouse, rat) is an endogenous peptide substrate for angiotensin converting enzyme (ACE) and ACE2; precursor to the vasoconstrictor peptide angiotensin II (Cat. No. 1158).

Technical Data for Angiotensin I (human, mouse, rat)

M. Wt 1296.5
Formula C62H89N17O14
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 484-42-4
PubChem ID 3081372
Smiles [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Angiotensin I (human, mouse, rat)

Solubility Soluble to 1 mg/ml in water

Product Datasheets for Angiotensin I (human, mouse, rat)

Certificate of Analysis / Product Datasheet
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References for Angiotensin I (human, mouse, rat)

References are publications that support the biological activity of the product.

Erdo (1976) Conversion of angiotensin I to angiotensin II. Am.J.Med. 60 749 PMID: 190881

Erdos and Skidgel (1990) Renal metabolism of angiotensin I and II. Kidney Int.Suppl. 30 S24 PMID: 2175370

Manabe et al (1989) Endothelium-dependent contractions induced by angiotensin I and angiotensin II in canine cerebral artery. J.Pharmacol.Exp.Ther. 251 317 PMID: 2795464

If you know of a relevant reference for Angiotensin I (human, mouse, rat), please let us know.

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Citations for Angiotensin I (human, mouse, rat)

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