7-Hydroxy-PIPAT maleate

Discontinued Product

Unfortunately 7-Hydroxy-PIPAT maleate (Cat. No. 0719) has been withdrawn from sale for commercial reasons.
Cat.No. 0719 - 7-Hydroxy-PIPAT maleate | C16H22INO.C4H4O4 | CAS No. 200722-46-9
Description: D3 agonist (D3 > D2)
Alternative Names: 7-OH-PIPAT
Chemical Name: (RS)-trans-7-Hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin maleate
Purity: ≥98% (HPLC)

Biological Activity

This ligand has uniquely high affinity and selectivity for the D3 receptor. 8-Hydroxy-PIPAT maleate (Cat. No. 0797) also available.

Licensing Information

Sold with the permission of the University of Pennsylvania

Technical Data

M. Wt 487.33
Formula C16H22INO.C4H4O4
Storage Desiccate at +4°C
Purity ≥98% (HPLC)
CAS Number 200722-46-9
PubChem ID 24978534
Smiles OC(=O)\C=C/C(O)=O.CCCN(C\C=C\I)C1CCC2=CC=C(O)C=C2C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 487.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.05 mL 10.26 mL 20.52 mL
5 mM 0.41 mL 2.05 mL 4.1 mL
10 mM 0.21 mL 1.03 mL 2.05 mL
50 mM 0.04 mL 0.21 mL 0.41 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Chumpradit et al (1993) Synthesis and optical resolution of (R)- and (S)-trans-7-hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin: a new D3 dopamine receptor ligand. J.Med.Chem. 36 4308 PMID: 8277513

Foulon et al (1993) Synthesis of (R,S)-2'-trans-7-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-amino]tetralin (trans-7-OH-PIPAT): a new D3 dopamine receptor ligand. J.Med.Chem. 36 1499 PMID: 8098771

Kung et al (1993) In vitro binding of a novel dopamine D3 receptor ligand: [125I]-trans-7-OH-PIPAT. Eur.J.Pharmacol. 235 165 PMID: 8519278

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Keywords: 7-Hydroxy-PIPAT maleate, supplier, D3, agonists, Dopamine, Receptors, dopaminergic, 7-OH-PIPAT, D3, Receptors, D3, Receptors, Tocris Bioscience

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