8-Hydroxy-PIPAT oxalate

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Cat.No. 0797 - 8-Hydroxy-PIPAT oxalate | C16H22INO.C2H2O4 | CAS No. 1451210-48-2
Description: High affinity 5-HT1A agonist
Chemical Name: (RS)-trans-8-Hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin oxalate
Purity: ≥98% (HPLC)
Literature (5)

Biological Activity

High affinity 5-HT1A receptor agonist (Kd = 0.38 nM).

7-Hydroxy Isomer also available.

Licensing Information

Sold with the permission of the University of Pennsylvania

Technical Data

M. Wt 461.3
Formula C16H22INO.C2H2O4
Storage Desiccate at -20°C
Purity ≥98% (HPLC)
CAS Number 1451210-48-2
PubChem ID 56972162
Smiles [H]OC(=O)C(=O)O[H].CCCN(C\C=C\I)C1CCC2=CC=CC(O)=C2C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
ethanol 37.13 100
DMSO 37.13 100

Preparing Stock Solutions

The following data is based on the product molecular weight 461.3. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.17 mL 10.84 mL 21.68 mL
5 mM 0.43 mL 2.17 mL 4.34 mL
10 mM 0.22 mL 1.08 mL 2.17 mL
50 mM 0.04 mL 0.22 mL 0.43 mL

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References are publications that support the biological activity of the product.

Zhuang et al (1993) Synthesis of (R,S)-trans-8-Hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin (trans-8-OH-PIPAT): a new 5-HT1A receptor ligand. J.Med.Chem. 36 3161 PMID: 8230102

If you know of a relevant reference for 8-Hydroxy-PIPAT oxalate, please let us know.

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Keywords: 8-Hydroxy-PIPAT oxalate, 8-Hydroxy-PIPAT oxalate supplier, High, affinity, 5-HT1A, agonists, Serotonin, Receptors, 0797, Tocris Bioscience

Citations for 8-Hydroxy-PIPAT oxalate

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