High affinity 5-HT1A receptor agonist (Kd = 0.38 nM).7-Hydroxy Isomer also available.
Sold with the permission of the University of Pennsylvania
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 461.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.17 mL||10.84 mL||21.68 mL|
|5 mM||0.43 mL||2.17 mL||4.34 mL|
|10 mM||0.22 mL||1.08 mL||2.17 mL|
|50 mM||0.04 mL||0.22 mL||0.43 mL|
References are publications that support the products' biological activity.
Zhuang et al (1993) Synthesis of (R,S)-trans-8-Hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin (trans-8-OH-PIPAT): a new 5-HT1A receptor ligand. J.Med.Chem. 36 3161 PMID: 8230102
If you know of a relevant reference for 8-Hydroxy-PIPAT oxalate, please let us know.
View Related Products by Product Action
Keywords: 8-Hydroxy-PIPAT oxalate, supplier, High, affinity, 5-HT1A, agonists, Serotonin, Receptors, 5-HT1A, Receptors, 5-HT1A, Receptors, Tocris Bioscience
Citations for 8-Hydroxy-PIPAT oxalate
Citations are publications that use Tocris products.
Currently there are no citations for 8-Hydroxy-PIPAT oxalate. Do you know of a great paper that uses 8-Hydroxy-PIPAT oxalate from Tocris? If so please let us know.
Reviews for 8-Hydroxy-PIPAT oxalate
There are currently no reviews for this product. Be the first to review 8-Hydroxy-PIPAT oxalate and earn rewards!
Have you used 8-Hydroxy-PIPAT oxalate?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.