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Neuroactive steroid, an endogenous modulator of GABAA mediated chloride ion conductance.
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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Harrison et al (1987) Structure-activity relationships for steroid interaction with the γ-aminobutyric acidA receptor complex. J.Pharmacol.Exp.Ther. 241 346 PMID: 3033209
Lambert et al (1995) Neurosteroids and GABAA receptor function. TiPS 16 295 PMID: 7482994
Keywords: 5a-Pregnan-3a-ol-20-one, 5a-Pregnan-3a-ol-20-one supplier, GABAA, Receptors, 1022, Tocris Bioscience
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