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Discontinued Product5α-Pregnan-3α-ol-20-one (Cat. No. 1022) has been withdrawn from sale for commercial reasons.
Biological Activity for 5α-Pregnan-3α-ol-20-one
Neuroactive steroid, an endogenous modulator of GABAA mediated chloride ion conductance.
Technical Data for 5α-Pregnan-3α-ol-20-one
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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 5α-Pregnan-3α-ol-20-one
References for 5α-Pregnan-3α-ol-20-one
References are publications that support the biological activity of the product.
Harrison et al (1987) Structure-activity relationships for steroid interaction with the γ-aminobutyric acidA receptor complex. J.Pharmacol.Exp.Ther. 241 346 PMID: 3033209
Lambert et al (1995) Neurosteroids and GABAA receptor function. TiPS 16 295 PMID: 7482994
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Keywords: 5a-Pregnan-3a-ol-20-one, 5a-Pregnan-3a-ol-20-one supplier, GABAA, Receptors, 1022, Tocris Bioscience
Citations for 5α-Pregnan-3α-ol-20-one
Citations are publications that use Tocris products.
Currently there are no citations for 5α-Pregnan-3α-ol-20-one.
Reviews for 5α-Pregnan-3α-ol-20-one
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.