3-Nitropropionic acid

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Cat.No. 4849 - 3-Nitropropionic acid | C3H5NO4 | CAS No. 504-88-1
Description: Irreversible mitochondrial respiratory complex II inhibitor
Purity: ≥97% (HPLC)

Biological Activity

Irreversible mitochondrial respiratory complex II (succinate dehydrogenase) inhibitor; induces autophagy in SH-SY5Y cells. Recapitulates Huntington's disease-like pathology and symptoms in primate and rodent models.

Technical Data

M. Wt 119.08
Formula C3H5NO4
Storage Store at +4°C
Purity ≥97% (HPLC)
CAS Number 504-88-1
PubChem ID 1678
Smiles OC(CC[N+]([O-])=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 11.91 100
ethanol 11.91 100

Preparing Stock Solutions

The following data is based on the product molecular weight 119.08. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 8.4 mL 41.99 mL 83.98 mL
5 mM 1.68 mL 8.4 mL 16.8 mL
10 mM 0.84 mL 4.2 mL 8.4 mL
50 mM 0.17 mL 0.84 mL 1.68 mL

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