Voltage-gated Sodium (NaV) Channel Peptides

Activators

Cat No Product Name / Activity
5941 OD1
Potent hNav1.4, rNav1.6 and rNav1.7 channel activator

Blockers

Cat No Product Name / Activity
4804 APETx2
NaV1.8 and NaV1.2 blocker; also blocks ASIC3 channels
4718 Huwentoxin IV
Selective NaV1.7 channel blocker
4913 Jingzhaotoxin III
Selective NaV1.5 channel blocker
4914 Phrixotoxin 3
Potent blocker of NaV1.2, NaV1.3 and NaV1.5 channels
4665 ProTx I
CaV3.1 channel blocker; also inhibits NaV1.8 and KV2.1
4023 ProTx II
Selective NaV1.7 channel blocker
5792 ProTx III
Potent Nav1.7 blocker; analgesic

Other

Cat No Product Name / Activity
5184 BDS I
Attenuates inactivation of sodium currents by acting on Nav1.7 and Nav1.3 channels; neuroprotective
1539 β-Pompilidotoxin
Slows neuronal Na+ channel inactivation