Cat. No. 5786
Chemical Name: 4-Cyano-N-(1,2-dihydro-1,3-dimethyl
Biological ActivityHigh affinity BRPF inhibitor (Kd values are 40, 210 and 943 nM for BRPF1B, 2 and 3, respectively). Also exhibits modest activity at BRD9 (Kd = 1130 nM). Exhibits selectivity for BRPF over 44 other bromodomains. Orally bioavailable.
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Certificate of Analysis / Safety Data Sheet
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Keywords: NI 42, supplier, NI42, Bromodomains, PHD, fingers, BRPF, inhibitors, inhibits, orally, available, Tocris Bioscience, Bromodomain Inhibitor products
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