NVS-CECR2-1

Cat. No. 5744new

NVS-CECR2-1 C27H37N5O2S [1992047-61-6]

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Chemical Name: N-Cyclopropyl-2-(propylsulfonyl)-6-(1-(2,2,6,6-tetramethylpiperidin-4-yl)-1H-indol-5-yl)pyrimidin-4-amine

Biological Activity

Potent and selective CECR2 (cat eye syndrome chromosome region, candidate 2) inhibitor (IC50 = 47 nM). Selective for CECR2 over a panel of bromodomains.

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the NVS-CECR2-1 probe summary on the SGC website.

Technical Data

M.Wt:
495.68
Formula:
C27H37N5O2S
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
1992047-61-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

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Keywords: NVS-CECR2-1, supplier, Potent, selective, CECR2, cat, eye, syndrome, chromosome, region, candidate, 2, inhibitors, inhibits, bromodomains, Tocris Bioscience, Bromodomain Inhibitor products

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