Cat. No. 5614
Chemical Name: 4-[5-[(1R)-1-[5-(3-Chlorophenyl)-3-
Biological ActivitymGlu5 antagonist. Displays discriminative effects in rats. Orally bioavailable and brain penetrant.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Swedberg et al (2014) AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects. J.Pharmacol.Exp.Ther. 350 212. PMID: 24876235.
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Citations are publications that use Tocris products.
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Keywords: AZD 2066, supplier, AZD2066, mGlu5, antagonists, metabotropic, glutamate, receptors, orally, bioavailable, brain, penetrant, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Antagonist products