FFN 206 dihydrochloride

Cat. No. 5043

FFN 206 dihydrochloride C12H14N2O2.2HCl [1883548-88-6]

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Chemical Name: 4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride

Biological Activity

Fluorescent VMAT2 substrate (IC50 app = 1.15 μM). Allows detection of VMAT2 subcellular locations in cell culture. Exhibits no detectable inhibition of DAT. Excitation maximum = 369 nm; emission maximum = 464 nm.

Licensing Information

Sold with the permission of Columbia University

Technical Data

M.Wt:
291.17
Formula:
C12H14N2O2.2HCl
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
>99 %
Storage:
Store at -20°C
CAS No:
1883548-88-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Hu et al (2013) New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2). ACS Chem.Biol. 8 1947. PMID: 23859623.

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Keywords: FFN 206 dihydrochloride, supplier, FFN206, dihydrochloride, Fluorescent, VMAT2, substrates, vesicular, monoamine, transporters, Tocris Bioscience, Fluorescent Probe products

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